Senior Clinical Sciences Manager

Immatics • Houston, TX

1d • Remote

About The Position

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Role Overview: We are seeking a Senior Clinical Sciences Manager to support the execution of our clinical trials, including the SUPRAME (IMA203-301) study. The Senior Manager will be responsible for supporting patient journey navigation, primarily for U.S. sites, and updating patient-facing and clinical trial materials. In addition, this role will contribute to protocol development, conduct literature research, support trial outcome reporting, and deliver training to internal and external stakeholders.

Requirements

• Bachelor’s degree in biology, pharmacy, or a related scientific field
• 7+ years of experience conducting literature research using clinical and medical databases
• Demonstrated experience supporting clinical trial activities, including protocol and patient-facing materials
• Experience training site staff or internal teams on clinical trial protocols and materials
• Legal eligibility to work in the United States is required.

Nice To Haves

• Master’s degree in biology, pharmacy, or a related scientific field
• Experience supporting regulatory documentation (e.g., IRB submissions, RFIs)
• Experience working in oncology or cell therapy clinical development
• Advanced ability to translate complex scientific data into clear, actionable insights and presentations
• Experience working cross-functionally in a global clinical trial environment

Responsibilities

• Serve as a key point of contact for clinical trial protocol and patient-facing material inquiries from sites and internal teams
• Support patient journey navigation, including proactive management of screening activities
• Contribute to authoring and updating clinical trial documents, including protocols, reports, and investigator materials
• Support preparation of responses for IRBs and regulatory authorities
• Deliver site training on clinical trial protocols and patient-facing materials (e.g., SIVs)
• Conduct literature research and develop presentations to support clinical activities
• Maintain accurate eTMF documentation and filing

Benefits

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibility and company match
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Number of Employees: 251-500 employees