Senior CADD Scientist

Genesis Molecular AI • San Diego, CA

1d • Hybrid

About The Position

Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Senior CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US.

Requirements

• PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD.
• Deep understanding of structure-based drug design and protein-ligand interactions.
• Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.
• Minimum of 2+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs.

Responsibilities

• Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents.
• Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts.
• Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches.
• Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making.
• Adapt to a fast-paced environment where innovation and quick iteration are encouraged.

Benefits

• Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees)
• Stock Option Eligibility
• 401(k) Plan
• Open PTO Policy
• Paid Company Holidays
• Subsidized lunch and snacks at our offices

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree