Senior Bioinformatics Engineer II

ModernaTX • Cambridge, MA

1d • Onsite

About The Position

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. Moderna is strengthening its international business services hub in Warsaw, supporting our growing global operations. We welcome professionals ready to help advance our mission and shape the future of mRNA medicines. In this role, you will help ensure the reliability, quality, and compliance of critical bioinformatics pipelines that support Moderna’s scientific and operational objectives. Working at the intersection of bioinformatics, software engineering, validation, and operational support, you will monitor system performance, identify deviations from established standards, and drive continuous improvements across the software ecosystem. You will play a key role in maintaining continuous software operations, supporting validation activities, enhancing automation capabilities, and collaborating with multidisciplinary teams to strengthen the robustness of scientific software platforms. This position also offers exposure to advanced digital technologies and opportunities to work alongside teams leveraging automation, data-driven processes, and emerging Generative AI-enabled solutions to improve operational efficiency.

Requirements

• Bachelor's degree in Computer Science, Engineering, or a related field and 10 + years of relevant work experience
• Strong programming skills, particularly in Python and Linux
• Excellent problem-solving and analytical skills
• Ability to work independently and as part of a team
• Experience using a bioinformatics workflow framework (e.g. NextFlow, Luigi, Snakemake, NextFlow preferred), version control systems (Git preferred), Cloud (AWS preferred) and containers (Docker preferred)
• Experience with Computer System Validation processes.
• Experience in a GxP environments and knowledge of regulatory compliance requirements

Nice To Haves

• Experience with bioinformatics software and an understanding of neoantigen therapies
• Proven experience in software quality assurance and quality control
• Effective time management, organization, and planning skills
• Flexibility; adaptability to frequent change
• Results oriented; ability to manage performance.
• Effective communication, both written and verbal
• Personal and shared accountability
• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Responsibilities

• Monitor bioinformatics pipelines and scientific software systems to identify deviations from established standards and recommend corrective actions.
• Support the development, refinement, and implementation of standards, methods, and procedures used to assess software quality and operational readiness.
• Collaborate closely with bioinformatics and software engineering teams to design, develop, and enhance automated testing capabilities that support continuous operation of bioinformatics pipelines.
• Monitor and maintain scientific software platforms to ensure reliable and uninterrupted performance.
• Troubleshoot, investigate, resolve, or appropriately annotate software and operational issues to support efficient incident management.
• Support computer system validation activities through the drafting, execution, and maintenance of qualification scripts, protocols, and associated validation documentation.
• Work independently and in partnership with development teams to identify software defects, resolve bugs, and implement system improvements.
• Provide on-call support to address urgent operational issues and minimize downtime.
• Develop, maintain, and continuously improve documentation related to software troubleshooting, issue investigation, issue resolution, and operational procedures.
• Improve and automate error reporting applications to increase visibility, efficiency, and system reliability.
• Continuously expand technical knowledge of scientific software platforms, bioinformatics technologies, and supporting infrastructure.
• Contribute to a culture of operational excellence, continuous improvement, compliance, and high-quality software delivery.

Benefits

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

What This Job Offers

• Job Type: Full-time
• Career Level: Senior