Senior Automation Engineer

Caris Life SciencesPhoenix, AZ
Onsite

About The Position

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins. Position Summary The Senior Automation Engineer is a technical leader and subject matter expert for laboratory automation and liquid-handling systems supporting high-throughput clinical workflows. This role owns automation solutions across the full lifecycle and partners with cross-functional teams to deliver scalable, compliant, and reliable automated laboratory processes.

Requirements

  • Bachelor's degree in Engineering, Computer Science, Laboratory Science, Biotechnology, or related field.
  • Minimum 3 years of hands-on liquid handler programming experience.
  • Experience with automated molecular biology workflows and NGS sample preparation.
  • Experience with equipment and method verification/validation.
  • Strong troubleshooting, communication, documentation, and project management skills.
  • Experience with liquid class development and process optimization.
  • Proficiency in Microsoft Office Suite.

Nice To Haves

  • Master's degree in a related discipline.
  • Experience in regulated CAP/CLIA, FDA, GLP, GMP, or ISO environments.
  • Programming experience in Python, C#, SQL, JavaScript, or similar languages.
  • Experience with LIMS, APIs, and laboratory data integrations.
  • ASCP certification or relevant laboratory credential.
  • Experience mentoring engineers and leading cross-functional teams.

Responsibilities

  • Lead design, development, testing, implementation, and lifecycle support of automated laboratory workflows.
  • Develop and optimize liquid handling methods and liquid classes.
  • Integrate automation platforms with instruments, LIMS, and software systems.
  • Execute feasibility, verification, validation, and qualification activities.
  • Author SOPs, protocols, reports, and quality documentation.
  • Troubleshoot complex hardware, software, robotics, and assay issues.
  • Drive throughput, reliability, and process improvement initiatives.
  • Provide technical support, mentoring, and project leadership.

Benefits

  • All job-specific, safety, quality, and compliance training are assigned based on the job functions associated with this position.
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