Senior Automation Engineer (Lab Automation Platforms)

Vertex Pharmaceuticals•San Diego, CA

5d•$124,000 - $186,000•Onsite

About The Position

We are seeking a senior, hands‑on Senior Automation Engineer to help define, evolve, and execute the technical vision for laboratory automation platforms. This role combines platform ownership and architectural leadership with deep, practical involvement in instrument integration, troubleshooting, and live lab operations. The ideal candidate has shaped automation platforms or workcell architectures that scale across instruments, workflows, and teams, while remaining close to the lab and accountable for reliability in production. You translate long‑term vision into pragmatic systems that scientists and operators trust. This is an onsite position in San Diego. Primary Stack: .NET (C#), JavaScript, Relational Databases

Requirements

PhD in software, computer sciences or related field and 2-5 years experience in life sciences, engineering or academia, or Master's Degree in software, computer sciences or related field and 5 years experience in life sciences, engineering or academia, or Bachelor's Degree in software, computer sciences or related field and 8 years experience in life sciences, engineering or academia
Significant experience with: C# / .NET JavaScript / TypeScript Relational databases (advanced SQL, schema design)
Proven experience defining and delivering technical vision for complex automation or platform systems.
Deep, hands‑on experience with laboratory or industrial automation.
Strong troubleshooting skills across software and physical systems.

Nice To Haves

Experience in drug discovery or high‑throughput laboratory environments.

Responsibilities

Automation Platform Vision & Ownership Help shape the technical vision, architecture, and standards for laboratory automation software and workcell integration.
Translate automation goals (scalability, reliability, flexibility) into concrete platform patterns and implementations.
Act as a technical steward, balancing near‑term operational needs with long‑term platform health.
Hands‑On Integration & Operational Support Design, implement, and support instrument drivers, control layers, and orchestration logic across diverse lab equipment.
Troubleshoot complex failures spanning software, robotics, instruments, networking, and data flows.
Support commissioning, validation, and rollout of new automation capabilities.
Serve as an escalation point for complex or systemic automation issues.
Reliability, Usability & Operator Experience Architect robust communication, error handling, recovery, and observability patterns.
Design systems that fail safely and recover predictably under real lab conditions.
Guide operator‑facing software to provide clear system state, actionable errors, and intuitive recovery workflows.
Use operator and scientist feedback to drive continuous improvement.
Data & Informatics Integration Shape data models and workflows supporting traceability, QC, and analytics across automated runs.
Influence relational database design and performance for workflows.
Collaborate with informatics teams to align automation data with enterprise systems.
Technical Leadership Provide technical leadership during live operations and incident response.
Mentor engineers and automation specialists.
Influence roadmaps, priorities, and investments in reliability and platform health.