Senior Associate Scientist, Neuroscience Discovery Biology

Bristol Myers Squibb • Needham, MA

1d • $105,040 - $127,287

About The Position

The Senior Associate Scientist, Neuroscience Discovery Biology, works within the Neuroscience TRC, which develops transformational therapeutics for neurodegenerative, neuromuscular, and neuropsychiatric diseases. The group uses internal and external partnerships across disease areas and treatment modalities, including small molecules, biologics, and genetic medicines. Its research focuses on causal human biology, matching therapeutic modalities to molecular mechanisms, and translational discovery toward clinical proof of concept.

The role uses advanced cellular and biochemical methods to address neuroscience project questions. The scientist independently designs, executes, and analyzes in vitro and ex vivo experiments supporting target validation, mechanism-of-action studies, and lead optimization; helps develop and optimize assays, disease models, and translational approaches; and produces and communicates high-quality data packages. The position collaborates with multidisciplinary project teams and contributes to troubleshooting and a collaborative, inclusive, scientifically rigorous laboratory environment.

Requirements

• Bachelor's degree and 4 or more years of academic or industry experience, or a master's degree and 2 or more years of academic or industry experience.

Responsibilities

• Use cellular and biochemical techniques, including human iPSC-derived cells, biochemical assays, transcriptomics, immunoassays, and high-content imaging, to address project questions.
• Independently design, execute, and analyze in vitro and ex vivo experiments supporting target validation, mechanism-of-action studies, and lead optimization.
• Contribute to development and optimization of novel assays, in vitro disease models, and translational research approaches.
• Generate high-quality data packages and communicate findings to project teams and functional leadership.
• Collaborate with biology, medicinal chemistry, DMPK, translational medicine, and computational biology teams.
• Participate in troubleshooting and propose solutions to scientific and technical challenges.
• Foster a collaborative, inclusive, and scientifically rigorous laboratory environment.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings, subject to plan terms and eligibility.
• Flexible Time Off for eligible U.S.-based exempt employees, subject to manager approval.
• Paid company holidays; the number and additional vacation or optional-holiday arrangements vary by employee category and location.
• Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer-hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Potential eligibility for discretionary incentive cash and stock opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior