Clinical/Development - Senior Associate Scientist

TalentBurst•Cambridge, MA

About The Position

The Senior Associate Scientist will join the Advanced In Vitro Models team and contribute to the development and application of human cell–based disease models and engineered in vitro systems to support therapeutic discovery. The role involves human iPSC culture and differentiation, molecular and cellular characterization, and the development and optimization of advanced in vitro models. The successful candidate will be detail-oriented, scientifically curious, and comfortable working in a collaborative, fast-paced research environment.

Requirements

BS with 4–6 years or MS with 2–4 years of relevant industry or academic experience.
Hands-on experience with human iPSC culture and differentiation.
Strong mammalian cell culture and molecular biology skills, with experience using RNA- and protein-based readouts.
Strong organizational and communication skills, attention to detail, and the ability to work independently and collaboratively.

Nice To Haves

Experience designing and executing CRISPR/Cas9 genome-editing workflows and validating engineered cell lines.
Experience with advanced imaging techniques, organoid culture, or other complex human cell–based systems.

Responsibilities

Maintain, expand, and differentiate human iPSCs into relevant cell types for disease modeling and therapeutic discovery.
Perform molecular and cellular characterization using techniques such as qPCR, RNA and protein analysis, imaging, sequencing, and functional assays.
Support the development, optimization, and characterization of advanced in vitro systems, including co-culture and 3D models.
Design and execute experiments, analyze data, troubleshoot technical challenges, and communicate conclusions clearly.
Maintain accurate experimental records and ensure high standards of data quality and reproducibility.
Present findings internally and collaborate effectively with cross-functional discovery teams.