Senior Associate Scientist

PfizerPearl River, NY
Onsite

About The Position

This laboratory-based position is in the Analytical Development group within Vaccines. The primary functions of this role are to develop analytical assays in support of the extensive vaccine portfolio and to support the Critical Reagents tasks. The individual will collaborate closely with scientists across the Early BioProcess Development (EBPD) to design and implement cell-based potency assays for multiple vaccine programs. The individual will participate in regular vaccine development meetings and represent the group on multidisciplinary teams.

Requirements

  • BS degree in biological science, microbiology, immunology, or related fields with 2+ years relevant laboratory experience; OR a master's degree with more than 0+ years of experience.
  • Background and experience in mammalian cell culture, DNA and RNA transfection, and reporter cell assays.
  • Experience with ELISA assay.
  • Experience with in vitro expression and flow cytometry.
  • Knowledge of innate and acquired immunity, with the ability to apply this knowledge to test novel adjuvants.
  • Proficiency in analytical software, including GraphPad Prism and SoftMax.
  • Proficiency in computer skills including Microsoft Word, PowerPoint, and Excel.
  • Strong organization skills
  • Strong verbal and written communication skills.
  • Permanent work authorization in the United States.

Nice To Haves

  • Experience with authoring development reports and lab methods
  • Experience in documenting experiments using Signals electronic lab notebook

Responsibilities

  • Provide laboratory-based support for assay development, including ELISA and cell-based assays to support potency assay development.
  • Perform in-vitro expression analysis of mRNA Drug Substance (DS) and Drug Products (DP) for multiple RNA vaccine programs.
  • Support sample testing for process development, formulation development, critical reagents characterization and on-going stability studies.
  • Analyze data using appropriate statistical software, such as GraphPad Prism and SoftMax
  • Support the Critical Reagents qualification testing, delivery, and documentation
  • Document experiments, data, and conclusions in an electronic lab notebook (ELN) contemporaneously.
  • Contribute to authoring technical documents, including development reports, analytical lab methods, and method qualification reports.
  • Review scientific and technical literature to stay current in the field.
  • Present data in meetings within the department

Benefits

  • 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
  • paid vacation, holiday and personal days
  • paid caregiver/parental and medical leave
  • health benefits to include medical, prescription drug, dental and vision coverage
  • Relocation assistance may be available
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