Senior Associate Scientist, Metabolism
About The Position
Pfizer's purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. Obesity is a growing health and economic burden worldwide. It is risk factor for other comorbidities including heart disease, stroke, Type 2 Diabetes Mellitus (T2DM), certain types of cancer, and higher mortality risk from COVID-19 infection. The Internal Medicine Research Unit (IMRU) is seeking a highly motivated non-PhD scientist with in vivo and molecular biology experience to support preclinical drug discovery efforts around obesity. The ideal candidate will be able to design and execute experiments, as well as analyze, interpret, and effectively communicate results. The candidate will work closely with their manager and other IMRU Pfizer scientists to support exploratory and portfolio efforts.
Requirements
- Bachelor’s degree in biology, pharmacology, biochemistry, molecular biology or other related discipline
- At least 3 years of lab experience in academia or in industry for Bachelor's.
- Comfortable working with rodents (minimum: handling, dosing)
- Familiarity with standard cell and molecular biology methods including but not limited to cell culture, siRNA and plasmid transfections, lentivirus preparation and transduction, immunoassays such as ELISAs and western blotting, and quantitative real-time PCR.
- Ability to use appropriate software to perform data analysis.
- Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, strong motivation with a dedicated work ethic.
- Excellent verbal and written communication skills.
- Creative, self-motivated and the ability to work independently including analysis and troubleshooting of experimental results and reviewing literature to formulate new approaches.
- Ability to work in vivarium with rodents.
- Permanent work authorization in the United States.
Nice To Haves
- Experience with in vivo food intake/ body weight studies, tissue collection; or measurements of physical function (max force, treadmill running).
- Knowledge of metabolism and pharmacology.
- Experience working in or collaborating with industry.
Responsibilities
- Perform in vivo/ ex vivo/ in vitro experiments.
- Conduct molecular biology experiments such as but not limited to transfection, gene expression analysis, immunostaining, ELISA and Western blotting.
- Capable of following assay protocols and analyzing and interpreting data.
- Compliance to laboratory safety and electronic notebook standards.
- Work effectively with peers to support projects.
- Identify and report any experimental problems, proactively troubleshoot causative factors, and implement necessary corrections following discussion with supervisor.
Benefits
- 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
- paid vacation, holiday and personal days
- paid caregiver/parental and medical leave
- health benefits to include medical, prescription drug, dental and vision coverage
- Relocation assistance may be available
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What This Job Offers
Job Type
Full-time
Career Level
Senior
