Senior Associate Scientist, Immunology

Sanofi•Waltham, MA

3d•$75,000 - $108,333•Onsite

About The Position

The Senior Associate Scientist reports directly to the Early-Stage Immunology Laboratory Director (ESI), Global Immunology (GI), Sanofi Vaccines R&D. This role participates in the development and execution of experiments in immunology projects to evaluate the potential of novel and early-stage vaccine candidates, within the given research areas and defined protocols. The Senior Associate Scientist may contribute to projects based in Marcy L’Etoile (France), Waltham or Orlando (US), while being affiliated with a specific site. The Senior Associate Scientist may be required to work on multiple projects. Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Requirements

Bachelor's OR Master's degree in Immunology, Microbiology, Biology, or a related life sciences/scientific discipline
Bachelor's degree holders: 3+ years of laboratory or related environment experience
Master's degree holders: 1+ year of laboratory or related environment experience
Academic and research experience will be considered

Nice To Haves

Experience with serum-based immunological assays for viral pathogens (microneutralization, ELISA, multiplex assays such as Luminex and MSD)
Experience with semi-automated microneutralization assays
Familiarity with automation platforms (e.g., Hamilton liquid handler)
Familiarity or hands-on experience with COVID-related assays or projects (strong plus)
Mammalian cell culture experience
Sample inventory management
Practical experience with use of electronic notebooks (Benchling)
Ability to coordinate animal studies
Knowledge of data analysis and visualization tools (e.g., Prism, SoftMaxPro)
Familiarity with multimode readers such as Cytation
Problem-solving and analytical thinking
Time management and ability to handle multiple priorities
Strong team spirit and collaborative mindset
Clear verbal and written communication skills
Adaptability and stress management

Responsibilities

Contribute to the progress of immunology projects
Design and perform experimental assays in compliance with study protocols and Standard Operating Procedures to achieve the goals outlined in the experimental design plan under the guidance of Team Members and ESI Subject Matter Experts
Participate in the quality check, data analysis, interpretation and documentation of the experimental assays
Synthesize and present concise scientific and data-based presentations with appropriate conclusions
Develop assays and perform testing of the samples from non-clinical studies in functional semi-automated and automated assays
Perform mammalian cell culture to support cell-based assays testing as required
Coordinate in vivo studies, prepare formulations for administration into animals and complete required Benchling registrations
Support development and execution of automation of the serological assays (ELISA and microneutralization) using Hamilton liquid handler platform (or alike)
Maintain laboratory equipment upkeep as assigned
Document experiments per required templates, procedures and timelines in Benchling
Manage and maintain critical sample inventories for animal study formulations, ensuring accurate tracking and timely availability throughout the study lifecycle.
Explore and help with implementation of new technologies to the GI function to enable better support to the ongoing projects with the state-of the art technological approaches.
Participate in quality documentation and technical reports, contribute to preparation of SOPs, abstracts and manuscripts as appropriate.
Present own work both internally at project team meetings and project reviews
Actively engage in internal scientific initiatives including R&D Days, Science Exchange, and scientific seminars to stay at the forefront of innovation and emerging developments
Monitor and report on activities within their scope
Proactively alert the Immunology project team to any issues or delays and propose a mitigation plan to minimize impact
Conduct the reporting of activities under their accountability and contribute to site, project team or sub team meetings to ensure effective communication and coordination within the site and the projects
Contribute to the writing of assigned key documents (incl. protocols, assay reports, monthly activity reports)
Master the execution of multiple activities and develop new experiments
Demonstrate technical proficiency in a broad array of experimental assays and technologies
Analyze relevant literature provided by Team Members and ESI Subject Matter Experts to become knowledgeable on specific projects and maintain their technical expertise
Develop new protocols and or/methodologies to solve complex problems and create innovative assays under the guidance of ESI Subject Matter Experts
Actively participate in Technology communities, contributing to knowledge sharing
Participate in laboratory daily management tasks (incl. ordering reagents and consumables, handling shipments)
Support training and technical mentoring, providing guidance to more junior personnel regarding protocol development and execution
Adhere to HSES policies for personal safety and handling of reagents/biologics/pathogens and stay compliant in applicable trainings
Identify and help to improve best practices in HSES operations