Senior Associate Scientist, Gene Engineering and Delivery

Bristol Myers Squibb • Seattle, WA

28d • Onsite

About The Position

The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. The Gene Engineering and Delivery team in the Cell Therapy Thematic Research Center is seeking a highly motivated scientist to advance next-generation cancer immunotherapies through molecular design, viral vector engineering, and gene delivery innovation. This role will focus on designing, cloning, characterizing, and producing viral vector constructs that enable development of CAR T cell therapies. The ideal candidate brings strong molecular biology expertise, hands-on cell culture experience, and a collaborative, problem-solving mindset in a fast-paced research environment.

Requirements

• Bachelor’s Degree 4+ years of academic and / or industry experience Or Master’s Degree 2+ years of academic and / or industry experience
• Exceptional molecular biology skills, including molecular assay development, molecular design and cloning of complex DNA constructs, PCR, RT-PCR, and mRNA and DNA preparation.
• Experience with tissue culture techniques, including transfection of mammalian cell lines and transduction of T cells.
• Excellent organization, time management, and problem-solving skills with strong attention to detail.
• Ability to independently design and troubleshoot experiments
• Outstanding written, visual, and oral communication skills

Nice To Haves

• B.S./B.A. degree in a scientific discipline and 2+ years of hands-on experience in relevant field of research

Responsibilities

• Design and clone DNA constructs to support CAR T cell therapy development.
• Culture mammalian cell lines for viral vector production, assessment, and gene delivery applications.
• Set up and run molecular characterization and cellular assays to evaluate viral vector performance.
• Develop, optimize, and document viral vector production and characterization protocols.
• Designs and executes experiments based on protocols.
• Collaborate with team members to assess the technical feasibility of novel gene delivery methods.
• Analyzes and interprets experimental data.
• Works within established procedures and in loosely defined problem-solving situations.
• Actively participates in troubleshooting of routine problems and initiatives related to continuous improvement or development of new approaches/technologies.
• Works under minimal supervision for both routine activities and non-routine activities.
• Makes decisions that impact own work and other group/team members.
• Participates on program/project teams, as needed.
• Maintain accurate, detailed electronic laboratory notebook records and supporting documentation.
• Summarize and present data in group meetings and written reports.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
• Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior