Senior Associate Scientist - Drug Product Development

Sanofi•Cambridge, MA

1d•$75,000 - $108,333•Onsite

About The Position

This position supports the development of oral solid dosage formulations for small molecule drug products. The successful candidate will contribute to the design, development, and optimization of preclinical formulations (conventional and enabling) and clinical solid oral dosage forms (tablet and capsule), from early-stage development through scale-up and technology transfer to GMP manufacturing. Working under the guidance of senior team members and in close collaboration with cross-functional CMC teams, the candidate will apply hands-on laboratory skills and foundational scientific knowledge to help advance drug candidates into clinical development. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

Requirements

Bachelor's degree OR Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biomedical Engineering, Materials Science, Food Science, or a related life science/scientific/engineering discipline
4+ years (Bachelor's holders) OR 2+ years (Master's holders) of hands-on experience in product or process development in a pharmaceutical, laboratory or related environment
Experience with oral solid dosage formulation (tablets and/or capsules)
Experience running dissolution studies using standard apparatus (USP2, USP4, USP7) and/or Pion equipment
Solubility testing experience
Academic or research experience will be considered but industry experience is required

Nice To Haves

Experience with enabling formulations such as amorphous solid dispersions, nanosuspensions, or lipid-based formulations
Excipient compatibility testing and formulation screening experience
Hands-on experience with tablet presses (rotary and/or single-station)
Experience with granulation equipment (high-shear, fluid bed, and/or roller compaction)
Experience with capsule filling machines and/or coating equipment
Working knowledge of powder characterization techniques
Familiarity with Design of Experiments (DoE) methodologies
Exposure to process scale-up and technology transfer activities
Experience working with external manufacturing or research partners
Strong problem-solving skills and scientific curiosity
Effective oral and written communication skills
Ability to work collaboratively in a cross-functional team environment
Good organizational skills with the ability to manage multiple tasks and projects simultaneously

Responsibilities

Support the design and development of oral solid dosage formulations (tablets, capsules, granules) for preclinical and clinical programs
Execute formulation studies including excipient compatibility testing, prototype development, and formulation optimization under guidance
Contribute to the development of conventional and enabling formulations (e.g., amorphous dispersions) to help address bioavailability challenges
Support formulation and process development activities, including granulation (wet and dry), blending, compression/tableting, and encapsulation
Assist in applying DoE methodologies to optimize formulation and process parameters, with guidance from senior scientists
Collaborate within the CMC team as a contributing team member, supporting defined deliverables and milestones
Work with Analytical, Biopharm, Quality, and Regulatory colleagues to support alignment on development strategies
Support Research team interactions to help evaluate molecular attributes relevant to drug delivery and formulation design
Author and review technical reports, batch records, and supporting documentation with guidance from senior staff
Ensure all documentation is accurate, complete, and compliant with requirements
Maintain awareness of current scientific literature relevant to assigned projects
Makes decisions that may require extrapolation of technical knowledge. Decisions generally impact own work and may impact the work group or project team.
Independently plans standard and moderately complex experiments with relevant controls, with limited guidance from supervisor or subject matter experts. Able to plan and manage a set of concurrent experiments.
Individual contributor. Understands the responsibilities of being a team member and adheres to appropriate documentation and safety practices.
Presents internally within the functional group and to other local functions. May present to project or cross-functional teams as appropriate.
Organizes own daily work to meet deadlines. Contributes to team objectives and short-term operational goals under supervision.