Senior Associate Scientist – Biotherapeutics and Vaccines Analytical Testing

Pfizer • St Louis, MO

2d • Onsite

About The Position

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist, you will be at the forefront of this mission, working within our Research & Development division. Your role will be pivotal in translating advanced science and technologies into therapies and vaccines that matter most. By leveraging cutting-edge design and process development capabilities, you will help accelerate the delivery of best-in-class medicines to patients globally, ultimately improving their lives.

Requirements

• BA/BS with 3 to 5 years of experience performing biotherapeutics testing in an R&D or GMP (preferable) environment.
• Master's Degree with 0 to 4 years of experience performing biotherapeutics testing in an R&D or GMP (preferable) environment.
• Strong documentation skills and attention to detail.
• Some experience with method validation and method transfer.
• Ability to extract relevant information from scientific literature.
• Proficiency in recording observations, facts, data, and conclusions during experimental work or cGMP investigations.
• Solid understanding of fundamental biochemistry, including functional group recognition and compound characterization.
• Experience using spectroscopic (e.g., UV-VIS, fluorescence spectroscopy) chromatographic techniques (e.g., HPLC/UPLC) or experience in bioassay techniques (e.g., ELISA or cell-based bioassays).
• Experience in GMP laboratory operations and logistics.
• Effective interaction with peers and leaders as part of a multi-disciplinary team.
• Strong evidence of growth mindset and ability to work as part of a diverse team.
• Strong verbal and written communication skills.
• Permanent work authorization in the United States.

Nice To Haves

• Understanding of software systems used in biotherapeutics testing environments (EMPOWER, Labware LIMS or ELN or similar, SoftMax).
• Good Laboratory Practices (part of GxP) and Good Manufacturing Practices (also cGMP) knowledge.
• Problem-solving skills and the ability to make decisions based on limited options or limited information.
• Initiative and proactive approach to tasks and projects.
• Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.

Responsibilities

• Conduct qualitative and quantitative analyses of various biotherapeutic products and vaccines, to determine their quality during manufacture and during determination of their shelf life.
• Perform analytical method lifecycle activities such as verification, qualification, validation, and transfer activities for complex biotherapeutics (mAb, mAb-like), antibody drug conjugates, therapeutic proteins, and vaccines.
• Maintain written records of all experimental work in compliance with GLP/GMP and departmental SOPs.
• Assist in the maintenance and renewal of laboratory instruments and systems and improve safe and effective working practices.
• Attend team meetings to present data and apply technical skills and knowledge to solve complex investigation problems.
• Work under moderate supervision with regular review and identify activities to support work group/project team goals.
• Contribute to the achievement of immediate work group goals and collaborate with other team members across the larger analytical organization.
• Prioritize work to meet project deadlines and ensure participation and contribution as a team member.
• Continuously improve safe and effective working practices in the laboratory environment.
• Perform and troubleshoot as necessary analytical assays, while applying these methods across a board range of early and late-stage products in a cGMP environment.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior