Senior Associate Scientist, AAV Cell Line Development (Contractor)

Asimov • Boston, MA

7d • $55 - $60

About The Position

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics. We're seeking a Senior Associate Scientist to join our Synthetic Biology team on a 6 month contract. The ideal candidate will have a proven track record performing AAV and/or lentiviral vector stable producer cell line development in an industry setting. They will be a key contributor to our team, participating in the creation of stable producer cell lines for AAV and/or lentiviral vector therapeutics and research projects to improve our cell line development workflows. They will also work closely with Asimov’s synthetic biology and process development teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.

Requirements

• B.S or M.S. in Biological Engineering, Virology, Cell Biology, Molecular Biology, or a related field
• 5+ years of hands-on experience in AAV and/or lentiviral vector producer cell line development in support of GMP production of cell or gene therapies
• Strong written and verbal communication skills required

Nice To Haves

• Experience performing transfections, viral transductions, flow cytometry, and quantitative gene expression analyses (ddPCR, qPCR, ELISA) is highly desired
• Experience with viral genome engineering, and/or host cell genome engineering related to virus production or producer cell line technologies is highly desired

Responsibilities

• Perform AAV and/or lentiviral vector stable producer cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment
• Perform biological assays including ddPCR, ELISA, and flow cytometry
• Support innovation through development of novel workflows and applications
• Support research projects to develop viral vector therapeutics with enhanced quality attributes such as empty/full ratio, potency and/or cell targeting
• Work effectively as part of a cross-functional team in support of a synthetic biology design platform
• Design experiments, analyze data, troubleshoot, and maintain detailed records
• Represent the cell line development function on project teams, making decisions for cell line activities and effectively communicating results, progress and plans

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Associate degree