Scientist – RNA Sequencing / ddPCR

Thermo Fisher Scientific•Boston, MA

2d•$35 - $43•Onsite

About The Position

Thermo Fisher Scientific's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

Requirements

Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’) OR Masters degree
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Digital PCR (ddPCR, dPCR)
qPCR
Bulk RNA-sequencing library preparation and sequencing
DNA/RNA extraction
Oxford Nanopore library preparation and sequencing workflows
Statistical analysis and data visualization using R, GraphPad Prism, JMP, and Microsoft Excel
Differential gene expression analysis using DESeq2
Pathway enrichment analysis using GSEA and Gene Ontology
Sequencing data quality control, interpretation, and reporting
Analysis of digital PCR and sequencing datasets to support method development and process characterization
Proficiency with Microsoft PowerPoint, Excel, and Word
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds
Able to work in non-traditional work environments.
Able to use and learn standard office equipment and technology with proficiency.
May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
Must be legally authorized to work in the United States without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.

Nice To Haves

NanoString nCounter

Responsibilities

Independently design, execute, troubleshoot, optimize, and interpret analytical method development experiments using digital PCR, qPCR, ddPCR, bulk RNA sequencing NanoString nCounter, Oxford Nanopore sequencing
Perform DNA/RNA extraction, sequencing library preparation, sequencer operation, digital PCR workflows, and other associated laboratory procedures with a high standard of technical rigor.
Design and conduct experiments to evaluate assay performance characteristics, including accuracy, precision, linearity, sensitivity, and technology comparisons.
Analyze and interpret data using R, GraphPad Prism, JMP, and related bioinformatics tools to support assay development, process characterization, and technology evaluation.
Organize, analyze, and summarize data for project updates, technical reports, study summaries, and internal presentations.
Author and review protocols, SOPs, technical reports, study documentation, and regulatory support documents.
Collaborate cross-functionally with partners in analytical development, process development, research, and other teams to support analytical strategy and project goals.
Operate, maintain, and troubleshoot laboratory instrumentation, including NextSeq 2000, NovaSeq X, PromethION 24, NanoString nCounter Prep Station/Digital Analyzer, and digital PCR platforms.
Maintain laboratory organization, instrument readiness, reagent inventory, and compliance with documentation and laboratory best practices.

Benefits

competitive remuneration
annual incentive plan bonus
healthcare
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO)
10 paid holidays annually
paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave)
accident and life insurance
short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount