Scientist, Ophthalmology

Regeneron Pharmaceuticals•Tarrytown, GA

5d•$93,900 - $153,300•Onsite

About The Position

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an independent and highly motivated bench Scientist to join our Ophthalmology group, supporting the development of therapeutics for ocular and autoimmune diseases. In this role, you will engage in innovative research as part of our discovery efforts, developing new in vitro assays and models to elucidate pathways involved in ocular autoimmunity and evaluating therapeutic candidates, while collaborating closely with teams across the organization. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

BS/MS degree in Biology, Cell Biology, Immunology, or a related field, with 4-5 years of experience working in a laboratory setting
Strong knowledge of molecular and cellular biology
Experience with tissue culture (maintenance of transformed and primary cells), in vitro and ex vivo cell-based assays, and multicolor flow cytometry
Experience with in vitro modification of cell lines and primary mouse and human cells
Training in proper handling and care of mice, and collection of blood and tissue samples

Nice To Haves

Expertise in immunology or ophthalmology
Experience with mouse models of inflammatory/autoimmune diseases

Responsibilities

Design, plan, and perform in vitro and in vivo studies using cell lines and mouse models to investigate, validate, and screen therapeutic targets
Run ELISA/MSD/Luminex, RT-PCR, and flow cytometry using mouse/human serum and tissue
Isolate tissues and cells from mouse and human samples for further functional and phenotypic characterization
Design and/or execute in vitro cell-based functional assays using primary or engineered cells
Work with mice, including antibody dosing through various routes, interim bleeds, and tissue collection/processing
Develop new methods or technologies to troubleshoot experiments
Analyze data and communicate findings to peers and management at group and cross-functional meetings
Write protocols and study reports, maintaining accurate electronic records