Scientist, Neuromuscular Research
About The Position
We are seeking a highly motivated Scientist to join our dynamic neuromuscular research group and advance research programs focused on neuromuscular disorders. The ideal candidate will leverage expertise in neuromuscular biology, biochemistry and molecular biology to investigate disease mechanisms, identify novel therapeutic targets, and evaluate candidate therapeutics. As part of a collaborative team, your work will have a direct impact on understanding and potentially treating neuromuscular disorders, fitting seamlessly into the broader mission of our organization to innovate and improve patient outcomes.
Requirements
- PhD with 0-2+ years of relevant academic or industry experience in muscle biology, physiology, or a related field.
- Strong scientific and technical background in muscle biology, disease pathophysiology, and translational research.
- Demonstrated hands-on experience with the following techniques: iPSC-derived and primary human myotube and cardiomyocyte culture
- In vivo muscle function assessment, including evoked force measures, treadmill and other relevant endpoints in neuromuscular disease models.
- Biochemistry and molecular biology techniques
- Statistical analysis using GraphPad Prism or similar data analysis software
- Ability to independently design, execute and trouble shoot experiments
- Excellent presentation and communication skills
Nice To Haves
- Strong scientific background in muscle biology and/or genetic neuromuscular disorders such as DMD and DM1.
- Direct experience with RNA therapies, antisense oligonucleotides, LNP
- Strong track record of scientific publications and presentations
Responsibilities
- Independently design, execute, analyze, and interpret experiments supporting neuromuscular research programs.
- Develop and optimize molecular and cellular assays in iPSC-derived and primary human skeletal and cardiac disease models to assess therapeutic activity and mechanism of action.
- Characterize muscle disease relevant phenotypes in rodent models.
- Present data clearly and concisely in team meetings and other cross-functional forums.
- Collaborate with internal teams and external partners to facilitate research progress.
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
