Scientist, Molecular Interactions, Discovery Biologics

Merck • Boston, MA

1d • $98,000 - $154,300 • Onsite

About The Position

We are seeking a highly motivated Scientist to join the Molecular Interactions team within Early Biologics Characterization at Discovery Biologics in Boston. In this hands-on laboratory role, you will apply a range of biosensor and biochemical technologies to characterize protein therapeutics and their targets, generating critical data that drives biologics discovery and candidate selection. Responsibilities include executing and optimizing fit-for-purpose binding assays to evaluate affinity, kinetics, epitope specificity, cross-reactivity, and molecular quality of biologic therapeutics. Additional duties may include protein conjugation, biophysical characterization studies, implementation of new technologies, and communication of results to cross-functional project teams. We are looking for a passionate and collaborative scientist with a strong sense of curiosity, a desire to solve challenging scientific problems, and a commitment to generating high-quality data. Join a team where innovation, scientific rigor, and cutting-edge technologies come together to advance the next generation of biologic medicines.

Requirements

• Bachelor's degree in Biomedical Sciences, Biochemistry, Bioengineering, Molecular Biology, or a related discipline with 2 years of postgraduate hands-on relevant laboratory experience OR Master's degree with 1+ year of hands-on relevant laboratory experience
• Hands-on experience executing SPR and BLI based assays on biosensor platforms including Carterra, Biacore, or Octet
• Understanding of protein-protein interaction analysis, including binding affinity, kinetics, and data interpretation
• Experience using scientific data analysis tools such as GraphPad Prism, Microsoft Excel, or equivalent software
• Demonstrated ability to execute experiments, analyze and interpret data, troubleshoot technical challenges, and communicate results effectively
• Strong organizational skills with the ability to manage multiple assignments in a dynamic, team-oriented environment
• Effective written and verbal communication skills

Nice To Haves

• Experience developing or optimizing assays using ELISA, Microscale Thermophoresis (MST), KinExA, or related technologies
• Experience with protein conjugation techniques
• Experience with automated liquid-handling systems
• Experience using flow cytometry or FACS
• Experience supporting biologics discovery, protein sciences, or therapeutic characterization programs

Responsibilities

• Executing and optimizing fit-for-purpose binding assays to evaluate affinity, kinetics, epitope specificity, cross-reactivity, and molecular quality of biologic therapeutics.
• Protein conjugation.
• Biophysical characterization studies.
• Implementation of new technologies.
• Communication of results to cross-functional project teams.

Benefits

• medical, dental, vision healthcare and other insurance benefits (for employee and family)
• retirement benefits, including 401(k)
• paid holidays
• vacation
• compassionate and sick days
• annual bonus
• long-term incentive

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level