Scientist Instructor
About The Position
The Instructor position requires advanced expertise in skeletal biology, bone marrow stromal and progenitor cell biology, osteoblast and osteoclast regulation, bone remodeling, inflammatory signaling, molecular biology, and translational musculoskeletal research. This specialized knowledge is normally acquired through a doctoral degree in a closely related scientific discipline and extensive postdoctoral research training. The position requires proficiency in advanced experimental methods used in musculoskeletal and translational research, including conditional genetic mouse models, lineage-tracing approaches, primary human cell studies, molecular biology techniques, flow cytometry, genomic and epigenomic profiling, and computational analysis of complex biological datasets. The role supports research programs within HSS’s musculoskeletal research enterprise, including projects focused on bone regeneration, skeletal cell biology, osseointegration, peri-implant biology, the bone marrow microenvironment, and mechanisms underlying orthopaedic disease and treatment outcomes. The laboratory investigates implant loosening, periprosthetic fibrosis, inflammatory responses associated with orthopaedic implants, and interactions between immune cells and skeletal tissues. The Instructor is expected to independently design, conduct, and interpret complex laboratory investigations involving skeletal biology, inflammation, bone remodeling, and implant-associated pathology.
Requirements
- Doctoral degree in a closely related scientific discipline.
- Extensive postdoctoral research training.
- Advanced expertise in skeletal biology, bone marrow stromal and progenitor cell biology, osteoblast and osteoclast regulation, bone remodeling, inflammatory signaling, molecular biology, and translational musculoskeletal research.
- Expertise in skeletal stromal and progenitor cell biology, osteoblast differentiation, inflammatory signaling, and bone marrow niche regulation.
- Proficiency with conditional genetic mouse models, lineage-tracing approaches, primary human cell studies, molecular biology techniques, flow cytometry, genomic and epigenomic profiling, and computational analysis of complex biological datasets.
Responsibilities
- Independently design, conduct, and interpret complex laboratory investigations involving skeletal biology, inflammation, bone remodeling, and implant-associated pathology.
- Support research projects focused on bone regeneration, skeletal cell biology, osseointegration, peri-implant biology, and the bone marrow microenvironment.
- Investigate mechanisms underlying implant loosening, periprosthetic fibrosis, and inflammatory responses associated with orthopaedic implants.
- Study interactions between immune cells and skeletal tissues and their contribution to disease progression and treatment outcomes.
- Contribute to research involving prosthetic joint infection, inflammatory bone loss, and bone remodeling.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
