Scientist, In Vivo Pharmacology

MSD • Boston, MA

5d • Hybrid

About The Position

The Quantitative Biosciences Department at our Company's Research Laboratories is seeking a highly motivated Scientist to join our In-Vivo Pharmacology group at our Research Labs in Boston. The successful candidate will be responsible for developing disease models, planning / designing and execution of in-vivo pharmacologic or mechanistic studies using disease models, collection / analysis of data, and report writing in support of research & development programs in immunology and oncology therapeutic areas.

Requirements

• M.S. in Immunology, Pharmacology, Biology, Biotechnology, Molecular and Cell Biology, Biochemistry, Bioengineering, or related STEM field with 1+ year of relevant postgraduate experience or B.S. with 3+ years of relevant post-graduate in-vivo experience, preferably in a pharmaceutical/ research laboratory setting.
• Hands-on experience with in-vivo models – particularly related to autoimmune disease or tumor immunology.
• Experience in PK/PD models, autoimmune/tumor efficacy experience.
• ELISA, Western blot, and flow cytometry and other immunological assay skills are desired.
• Working knowledge using standard data analysis tools such as Graph Pad Prism, FlowJo, etc., and Microsoft programs.
• Excellent written and interpersonal communication skills and the ability to collate the results and make a presentation to the stakeholders.
• The ability to work independently, as well as collaboratively with peers within and across departments is expected.

Responsibilities

• Plan, design and execute in-vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology.
• Characterize and optimize in vitro, ex vivo or in vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.
• Run validation and research operating plan (ROP) assays for test articles with appropriate benchmarks.
• Maintain timely, accurate laboratory records of activities & comply with good documentation practices.
• Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.

Benefits

• The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
• Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.
• More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level