Scientist, In Vivo Pharmacology

Merck • Boston, MA

1d • Hybrid

About The Position

The Quantitative Biosciences Department at our Company's Research Laboratories is seeking a highly motivated Scientist to join our In-Vivo Pharmacology group at our Research Labs in Boston. The successful candidate will be responsible for developing disease models, planning / designing and execution of in-vivo pharmacologic or mechanistic studies using disease models, collection / analysis of data, and report writing in support of research & development programs in immunology and oncology therapeutic areas.

Requirements

• M.S. in Immunology, Pharmacology, Biology, Biotechnology, Molecular and Cell Biology, Biochemistry, Bioengineering, or related STEM field with 1+ year of relevant postgraduate experience or B.S. with 3+ years of relevant post-graduate in-vivo experience, preferably in a pharmaceutical/ research laboratory setting.
• Hands-on experience with in-vivo models – particularly related to autoimmune disease or tumor immunology.
• Experience in PK/PD models, autoimmune/tumor efficacy experience.
• ELISA, Western blot, and flow cytometry and other immunological assay skills are desired.
• Working knowledge using standard data analysis tools such as Graph Pad Prism, FlowJo, etc., and Microsoft programs.
• Excellent written and interpersonal communication skills and the ability to collate the results and make a presentation to the stakeholders.
• The ability to work independently, as well as collaboratively with peers within and across departments is expected.

Responsibilities

• Plan, design and execute in-vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology.
• Characterize and optimize in vitro, ex vivo or in vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.
• Run validation and research operating plan (ROP) assays for test articles with appropriate benchmarks.
• Maintain timely, accurate laboratory records of activities & comply with good documentation practices.
• Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.

Benefits

• The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
• We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level