Scientist, In Vivo CAR-T Pipeline
About The Position
Legend Biotech is seeking a Scientist, In Vivo CAR-T Pipeline as part of the Research and Development team based in Philadelphia, PA. Legend Biotech is a global leader in the development of innovative cell-based therapies. We are seeking a highly motivated Scientist to join our growing in vivo CAR-T development team. This role provides the opportunity to make a direct scientific impact by advancing our in vivo CAR-T platform from early discovery through preclinical development. The successful candidate will bring deep technical expertise in cell&gene therapy, along with a strong foundation in immunology and virology. You will work in a highly collaborative environment alongside research and early development teams to translate novel scientific concepts into robust therapeutic candidates. This role requires scientific rigor, hands-on execution, intellectual curiosity, and the ability to thrive in a fast-paced research setting. This is a fully onsite, lab-based position located in Philadelphia, PA.
Requirements
- PhD in Immunology, Cell Biology, Molecular OR Master’s degree with 3–6+ years of relevant experience
- Hands-on experience in immunology, cell therapy, gene therapy, or related fields
- Experience with viral vector systems (especially lentivirus) is highly preferred
- Industry or postdoctoral experience is a plus
Responsibilities
- Design, plan, and execute experimental studies to advance cell and gene therapy platforms and pipeline programs.
- Conduct and analyze in vitro and in vivo studies to assess product potency, efficacy, and safety.
- Develop, optimize, and troubleshoot experimental assays, including: Cell line engineering, Cell-based functional and cytotoxicity assays, ELISA and PCR-based assays, High-throughput binder screening, Viral vector packaging and titration.
- Analyze and interpret complex datasets and maintain accurate experimental documentation.
- Prepare clear, high-quality reports and presentations and communicate findings to internal research and cross-functional teams.
Benefits
- These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
