Scientist, In Vitro-Radioconjugate
About The Position
At AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life. Position Overview: We are seeking a highly motivated Scientist with a proven track record of scientific excellence to join our radioconjugate (RC) team in the Oncology Targeted Delivery group within AZ Early Oncology Discovery in Hamilton, Canada. You will be a key member of a team working to develop novel, targeted radioconjugate therapies and advance them through early pre-clinical development. You will bring your theoretical and practical expertise to support platform and pipeline RC projects, working with a cross-functional team to deliver pre-clinical datasets to support pipeline progression and platform development. You will have the opportunity to present data and represent the team in project team meetings, platform meetings, and other internal forums.
Requirements
- Bachelor's Degree in a related field along with at least 6 years proven experience or a Master’s degree with a minimum 2 years of experience. Recent Master’s graduates with extensive prior experience in a relevant area may be eligible.
- Extensive knowledge of cell biology, molecular biology, and/or biochemistry in the context of cancer biology, with a desire for continued learning.
- Experience with routine cell culture, particularly culture of tumor cells.
- Expertise in molecular- and cell-based methodologies, such as cytotoxicity assays, binding and internalization assays, multicolor flow cytometry, fluorescent and live cell microscopy, ELISA, and Western blotting.
- Works independently with minimal direction.
- Excellent communication, presentation, and interpersonal skills and evidence of delivery in a team-oriented, collaborative environment.
Nice To Haves
- Ph.D. degree.
- Deep conceptual understanding of cancer biology is preferred.
- Background in the biopharmaceutical industry is preferable but not required.
- Experience in molecular cloning and cell line engineering is highly desirable.
- Candidates with experience related to radiation biology, radiochemistry, or radiopharmaceutical therapies would be preferable.
- A proven record of productivity; contributions to scientific publications in peer-reviewed journals.
Responsibilities
- Develop, invent, conduct, troubleshoot, and analyze in vitro experiments to validate tool reagents, investigate target biology, and dissect the mechanism of action of these novel cancer therapeutics.
- Support cross-functional teams and work alongside project leaders to ensure the timely generation and dissemination of critical program data.
- Stay current with technical and scientific expertise in tumor biology and cancer modelling.
- Work with radioisotopes with fast learning of “hot” in vitro assays.
- Conduct experiments, analyze data, and prepare results for internal and external presentations and regulatory filings.
- Ensure own work, and work of peers, follows Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations.
Benefits
- Annual base salary for this position ranges from 82,377.60 to 108,120.60.
- Annual Variable Pay Bonus/Short Term Incentive opportunity.
- Eligibility to participate in our equity-based long-term incentive program (if applicable to role).
- Competitive Flex Benefits & Retirement Savings Program.
- 4 weeks’ paid vacation.
- Annual Personal Days.
- Contract Benefits Program (for Fixed Term Contract/Temporary positions excluding students).
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Senior
