Specialist, 3DT Biofabrication Scientist (Cambridge, MA)

Merck • Cambridge, MA

3d • Hybrid

About The Position

We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. In this role, the scientist will perform hands-on experimentation and provide support to advance the team’s biofabrication efforts. This position is based on-site in Cambridge, MA, supporting day-to-day laboratory workflows and assisting with model development within a collaborative research environment.

Requirements

• Minimum of 2 years of experience in mammalian cell culture and aseptic technique.
• Experience preparing and handling biomaterials or hydrogels for 3D culture applications.
• Experience working with MPS models, bioprinted platforms, or other 3D cell culture technologies.
• Familiarity with basic microscopy techniques for assessing cell health and experimental progress.
• Strong attention to detail, organizational skills, and accurate documentation practices.
• Demonstrated ability to execute experimental protocols and work with collaborators.
• Ability to work on-site, follow established protocols, and meet deadlines.
• Enthusiastic, self-motivated, and eager to learn new workflows.

Nice To Haves

• Experience with stem cell culture or differentiation workflows.
• Experience with stem cell-derived organoid models.
• Experience working with MIMETAS organ-on-chip, or similar high throughput, platform.
• Experience working in pharmaceutical drug discovery or development.
• Data analysis experience using Matlab, R, and/or Python.
• Experience with nucleofection.

Responsibilities

• Support the biofabrication and maintenance of microphysiological systems and bioprinted models.
• Perform routine mammalian cell culture while maintaining a high level of aseptic technique.
• Prepare and handle hydrogels/ECM for use in 3D culture (MPS and bioprinted) platforms.
• Assist in immunofluorescence staining, imaging, and analysis workflows.
• Reconstitute, aliquot, and prepare reagents and media.
• Execute multi-step experimental protocols and workflows.
• Document experimental procedures, observations, and results in electronic lab notebook.
• Assist with inventory management, ordering, and general lab maintenance.
• Support both general and project-specific laboratory operations as project needs evolve.
• Collaborate across different functional teams/locations.

Benefits

• medical, dental, vision healthcare and other insurance benefits (for employee and family)
• retirement benefits, including 401(k)
• paid holidays
• vacation
• compassionate and sick days
• annual bonus
• long-term incentive

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Associate degree