Scientist II, Precision Medicine TA
About The Position
The Precision Medicine Immunology Department is seeking a highly motivated Scientist with a background in immunology or immuno-oncology and experience in single-cell or spatial genomics, molecular biology, and cell biology to join the Translational Research team. This individual will support clinical biomarker discovery by profiling clinical and preclinical samples using single-cell and spatial omics approaches to better understand drug mechanisms of action and pharmacodynamics, while helping drive data-informed patient selection strategies. The role will contribute to drug development programs across inflammatory and autoimmune disease areas, including Dermatology, Gastroenterology, Rheumatology, and Fibrosis, spanning late-stage discovery through clinical trials. The successful candidate will join a growing translational research group and collaborate with cross-functional teams both internally and externally.
Requirements
- B.S. & typically 7+ years, M.S. & typically 5+ years of relevant industrial biotechnology experience in Immunology, cell & molecular biology, pharmacology, pathology, or other relevant biological sciences.
- Broad technical expertise in molecular and cell biology assays, with specialization in scRNA-seq, CITE-seq, and snRNA-seq across blood and tissue samples.
- Expertise in executing spatial omics experiments using CosMx, Xenium, and Visium platforms, integrated with deep expertise in molecular pathology techniques such as IHC and ISH.
- Strong organizational skills, with a demonstrated ability to prioritize tasks and allocate resources to meet aggressive timelines.
- A robust track record of scientific writing, ensuring high-quality documentation and verbal reporting of technical findings.
Responsibilities
- Independently lead the design, execution, and analysis of complex genomic profiling experiments, including scRNA-Seq, CITE-Seq, snRNA-Seq, and spatial transcriptomics/proteomics.
- Proactively identify technical artifacts, interpret quality control results, optimize assay performance, and ensure high quality and reproducible data delivery on timely deadlines.
- Stay at the forefront of the single-cell and spatial genomics field by surveying, evaluating, testing and validating novel scientific methodologies.
- Present work plans and acquired data clearly and precisely to cross-functional stakeholders through formal written reports and verbal updates.
Benefits
- paid time off (vacation, holidays, sick)
- medical/dental/vision insurance
- 401(k)
- short-term incentive programs
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
