Scientist II/III, Antibody Kinetics Biotherapeutics

BoehringerPRD•Brampton, ON

7d•$75,000 - $147,000•Onsite

About The Position

Boehringer Ingelheim is seeking a Scientist II/III to join the Antibody Generation Group within the Biotherapeutics Department in Ridgefield, CT. This role focuses on designing, executing, and interpreting Surface Plasmon Resonance (SPR) experiments to characterize binding interactions and kinetics of biotherapeutic modalities. The position involves applying advanced kinetic data analysis to inform lead selection, affinity maturation, and developability assessments in biotherapeutic discovery programs, aiming to generate best-in-class and first-in-class therapeutics. The role contributes to R&D discovery research, implements protocols, and provides technical expertise. As an employee, you will contribute to product discovery, development, and delivery, with opportunities for international collaboration and professional growth. The company supports employees through competitive compensation, benefits, and a focus on work-life balance.

Requirements

Bachelor’s degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline or Master’s degree from an accredited institution in related scientific discipline or equivalent experience in related field (for Scientist II)
Master’s degree in a related scientific discipline with 3+ years of industry experience or Bachelor’s degree with 6+ years or equivalent experience in molecular/cellular biology or biochemistry (for Scientist III)
Working knowledge of SPR-based technologies and the application of this technology in the drug discovery process to support project efforts, ranging from hit identification to mechanism- of-action studies is preferred
Knowledge of assay development methodologies for SPR specific instrumentation (BiacoreT200/S200, Biacore8K) supported by hands-on experience is preferred
Experience performing assay data capture and analysis using software such as, Biacore Insight, Spotfire, and Prism is beneficial
Ability to work independently as well as within a collaborative team environment with excellent writing, presenting and communication skills
Good record-keeping and organizational skills with exceptional attention to detail
Able to learn quickly and excel in a fast-paced work environment; self-motivation, adaptability and positive attitude
Must be legally authorized to work in the United States without restriction.
Must be willing to submit to a background investigation, including verification of your past employment, criminal history, and educational background.
Must be willing to take a drug test and post-offer physical (if required).
Must be 18 years of age or older.

Responsibilities

Independently design, execute, and interpret routine SPR experiments to characterize antibody-antigen interactions, generating high-quality kinetic data that supports antibody discovery and research objectives.
Apply established kinetic analysis approaches to evaluate binding interactions, analyze experimental data, draw scientific conclusions with input from supervisor and technical teams as appropriate, and effectively communicate results to project teams and at internal meetings.
Demonstrate a clear understanding of assigned assays and generated data, including their application within the antibody discovery process, ensuring accurate interpretation, documentation, and reporting of results.
Complete routine laboratory procedures independently and efficiently, requiring limited guidance on technical protocols and experimental execution.
Operate, troubleshoot, and maintain SPR instrumentation and associated laboratory equipment, ensuring instrument performance and data integrity.
Contribute to the evaluation and implementation of new SPR methodologies, technologies, and best practices to enhance assay performance, efficiency, and data quality.
Support laboratory excellence through process improvements, organization, and adherence to established workflows that promote operational effectiveness and reproducible results.
Collaborate with cross-functional discovery teams to provide data-driven insights that support project progression and decision-making.
Comply with applicable regulations, SOPs, and company policies, maintaining accurate scientific records and performing all work in a safe and compliant manner.