Scientist II, Analytical Development
About The Position
At Biogen, we are advancing science to deliver innovative therapies that transform patients’ lives. We are seeking a Scientist II to join our Analytical Development team as a Liquid Chromatography (LC) Subject Matter Expert (SME) and Analytical Project Lead. This role is pivotal, leveraging deep technical expertise in LC method development alongside leadership in analytical strategy across synthetics programs. Situated in Cambridge, MA, this lab-based position plays a crucial part in driving forward the development of synthetic drug substances and products, ensuring robust, stability-indicating methods. Your contributions will be vital to our mission, interfacing with various teams and shaping the analytical landscape of our drug development efforts.
Requirements
- Ph.D. with 0-3 years of relevant experience in pharmaceutical or biotech settings
- M.S. with 4+ years of relevant experience in pharmaceutical or biotech settings.
- BS with 6+ years of relevant experience in pharmaceutical or biotech settings
- Deep expertise in small molecule LC method development, with strong experience in HPLC/UHPLC and familiarity with LC-MS.
- Proven ability to lead analytical activities for drug development programs.
- Strong knowledge of ICH guidelines and experience working within regulated (GMP/GLP) environments.
- Excellent problem-solving, communication, and cross-functional collaboration skills.
Nice To Haves
- Experience with oligonucleotides and/or peptides.
- Advanced MS techniques (e.g., LC-MS/MS, HRMS).
Responsibilities
- Serve as the LC subject matter expert, leading method development, optimization, qualification, and troubleshooting (HPLC, UHPLC, LC-MS).
- Develop robust, stability-indicating methods for synthetic drug substances and products.
- Provide technical support to inform analytical strategy for development programs from early to late stage.
- Collaborate cross-functionally with CMC, formulation, process development, and quality teams.
- Provide oversight of analytical activities at CDMOs, including method validation, transfer, and lifecycle management aligned with regulatory expectations.
- Participate in mentoring and knowledge-sharing activities to support analytical capability building within the organization.
- Contribute to programs involving emerging modalities (e.g., oligonucleotides and peptides).
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Manager
Education Level
Ph.D. or professional degree
