Scientist I, Genotox (Contract)
About The Position
As a Scientist I on our Genomic Safety team, you will design, develop, and deploy cutting-edge assays to characterize the off-target landscape of our Gene Writer therapeutics at the intersection of molecular biology, next-generation sequencing, and translational safety science. You bring hands-on experience with NGS workflows, off-target discovery platforms, and PCR-based verification methods, and you thrive in a fast-moving environment where scientific rigor and program momentum go hand in hand. You are equally comfortable at the bench and in cross-functional discussions, communicating your findings clearly to genomic safety, computational biology, and regulatory colleagues.
Requirements
- PhD with 0-2 years of experience in academic or industry setting, MS with 6+ years of experience or BS with 8+ years of experience
- Broad knowledge of genome editing technologies and associated off-target discovery assays
- Genomic assay development or deployment experience for off-target discovery, verification and structural variation assessment
- Familiarity with NGS workflows and library preparation
- Deploying PCR-based off-target verification assays such as rhAmpSeq and Hybrid Capture Sequencing
- Developing and deploying unidirectional/ligation-mediated PCR assays
- Assay related molecular biology techniques including DNA extraction, nucleic acid quality assessment and primer design
- Basic cell biology skills including cell line culture and manipulation techniques (electroporation and transfection)
- Strong written and verbal communication skills
Responsibilities
- Developing and deploying assays for genomic safety assessment for the development of Gene Writer candidates
- Developing, deploying and analyzing NGS-based assays for off-target discovery and verification
- Examining genome structural variants using optical and molecular methods
- Working collaboratively with genomic safety, molecular assay, computational biology and regulatory sciences teams to advance Tessera’s therapeutic programs
- Contributing to scientific report writing, translating complex experimental findings to support regulatory and research goals
Benefits
- Pay Range: $52.00 - $58.00 USD per hour
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
