Scientist I, Downstream Process Development - Biologics - Eurofins CDMO Alphora, Inc.

Eurofins•Mississauga, ON

166d•CA$80,000 - CA$80,000•Onsite

About The Position

We are seeking a motivated and technically driven Scientist I, Downstream Process Development to join our growing Process Development team. In this role, you will contribute to the design and optimization of purification and bioconjugation processes for a wide variety of therapeutic proteins and novel biologics. Working closely with senior scientists and cross‑functional partners, you will support key laboratory studies involving chromatography, tangential flow filtration (TFF), filtration, and nanofiltration, while also helping scale processes toward larger‑volume operations. This is an exceptional opportunity for someone early in their career who is passionate about bioprocessing, enjoys hands‑on lab work, and wants to play a direct role in advancing innovative therapeutics from concept to clinic. The Scientist I - Downstream Process Development, is involved in the development of novel biologics and therapeutics by assuming a crucial role in the design of purification and bioconjugation processes for a wide range of proteins. The successful candidate will play a key role in laboratory studies for the development of a range of downstream processing steps including chromatography, tangential flow filtration (TFF), filtration, and nanofiltration amongst other steps while being able to communicate progress to internal stakeholders. The ideal candidate will also play key roles in scaling up processes. At Eurofins CDMO Alphora Inc., our mission is to harness the power of biotechnology and bioprocessing to create innovative complex medicines that will improve the lives of patients worldwide. With a dedicated team of experienced scientists, motivated technologists, and state-of-the-art process development (PD) facility, we are thrilled to be at the forefront of the biopharmaceutical CDMO industry in Canada. Join us on this exciting journey as we push the boundaries of scientific research and provide hope to our most vulnerable.

Requirements

Minimum Master’s degree with 3+ years of experience or PhD
Working knowledge of protein chemistry and protein purification along with self-directed learning and a willingness to grow one’s knowledge.
Experience with development and execution of chromatography process steps using UNICORN control software.
Experience with carrying out ultrafiltration and diafiltration studies using TFF.
Experience in and understanding of aseptic techniques in laboratory setting.
Knowledge in bioprocess engineering principles underlying effective scale-up design.
Knowledge of filtration and clarification steps in development and optimization.
Understanding of how to implement Design of Experiments (DoE) and Quality by Design (QbD) in the development of unit operations.
Understanding of Current Good Manufacturing Practices (cGMP) in biomanufacturing.
Being a key point of contact and Subject Matter Expert (SME) for scientific studies in the PD lab, communicating scientific information succinctly to a range of audiences.
Strong interpersonal skills and ability to work collaboratively as a member of a cross-functional team.
Excellent communication, GMP documentation, and organizational skills.
Strong problem-solving skills.

Nice To Haves

Knowledge of protein bioconjugation

Responsibilities

Serve as a Subject Matter Expert (SME) in downstream processing principles and best practices.
Apply bioprocess engineering and protein chemistry knowledge to design and optimize chromatography, TFF, and filtration studies.
Contribute to the design and execution of protein bioconjugation development activities.
Draft and review technical documents, including batch records, experimental procedures, data summaries, and scientific reports.
Communicate research findings clearly and confidently to internal teams and project stakeholders.
Support continuous improvement initiatives to deliver robust, scalable, and cost‑effective downstream processes for clients.
Perform hands‑on laboratory execution of planned studies, from buffer preparation to purification runs.
Record raw data in accordance with GDP/GLP standards, analyze results, and help refine experimental designs.
Write and review SOPs related to downstream process equipment, unit operations, and batch record documentation, following industry guidelines (GMP, HSE, IP).
Collaborate across functional teams—including analytical, upstream, engineering, and quality—to advance projects and support equipment qualification activities.
Independently plan, troubleshoot, and report on laboratory work with minimal supervision.
Assist in maintaining a well‑run laboratory by performing basic equipment upkeep and ordering consumables.