Scientist I, Cell and Molecular Biologist

AbbVieNorth Chicago, IL

About The Position

AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical and cell-based assays to support multiple programs.

Requirements

  • Bachelor’s Degree with 5 years of experience, or Master’s Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology or related discipline with significant research experience.
  • Proficiency in tissue culture, cellular & biochemical in vitro assay development and molecular biology techniques (e.g Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus)
  • Background in drug discovery, pharmacology and assay development.
  • Organizational skills and experience with computer programs, including Microsoft Excel, Powerpoint, GraphPad, FlowJo, etc.

Nice To Haves

  • Understanding and application of methods of antibody characterization and/or antibody-drug conjugates.
  • Knowledge and experience with a broad range of assays to characterize targeted protein degradation
  • Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE etc.)

Responsibilities

  • Design and execute in vitro studies to assess novel antibody-drug conjugates
  • Analyze and interpret experiments and present data to the broader project team and group meetings.
  • Propose relevant follow-up experiments as needed.
  • Troubleshoot and/or optimize experimental procedures as needed to further the program goals.
  • Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications
  • Work independently in a fast paced, multi-tasking environment as part of a diverse research team.
  • Collaborate with cross-functional teams to advance programs from early discovery to preclinical development

Benefits

  • paid time off (vacation, holidays, sick)
  • medical/dental/vision insurance
  • 401(k)
  • short-term incentive programs
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