Scientist I, Biochemistry

Neomorph•San Diego, CA

10h

About The Position

We are looking for a hands-on, team-oriented Scientist I to support protein science efforts to develop molecular glue therapies to target previously undruggable proteins. At Neomorph, we combine biology, chemistry, and the molecular sciences in a collaborative, fast-moving environment to translate bold ideas into transformative medicines. This role will focus on biochemical experimentation to enable targeted protein degradation programs from early discovery through preclinical development.

Requirements

Ph.D. in Biochemistry or related field with 0–2 years of experience, MS with 5+ years of relevant industry experience or BS with 10+ years of relevant industry experience.
Strong hands-on experience in protein expression and purification.
Proven proficiency with AKTA FPLC systems.
Experience with large protein complexes for biochemical characterization.
Proficiency in standard cell and tissue culture techniques.
Apply various assay formats, including protein-ligand and protein-protein interaction techniques (such as HTRF, DSF, AlphaScreen, among others).
Highly collaborative mindset with the ability to work effectively in cross-functional teams.
Comfortable operating in a dynamic, evolving biotech environment with shifting priorities.
Strong attention to detail, ownership of work, and enthusiasm for learning.

Nice To Haves

Experience in the protein degradation field is a plus

Responsibilities

Purify recombinant E3 ligases and disease relevant proteins for biochemical studies.
Develop, optimize, and execute biochemical and cell-based assays for ligand identification, lead discovery, and structure activity relationship studies.
Analyze experimental data and clearly communicate results to project teams.
Work closely with biologists and chemists to advance shared project goals.
Maintain clear, reproducible experimental records and contribute to a culture of scientific rigor.
Develop new techniques and advances in protein science and targeted protein degradation.

Benefits

Industry competitive compensation
Annual target bonus
Stock options
401K plan
Career advancement opportunities
Monthly town halls to share business and scientific updates
Work Hard, Stay Well
Comprehensive medical, dental, and vision plans for employees and their dependents
Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
Employee Assistance Program
10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
Supplemental pay for Pregnancy Disability Leave
Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care
Lifestyle
Casual work environment
Volunteer days off each year to spend time contributing to causes you care about
Flexible work schedule
Access to onsite gym
Onsite space to store your bicycle (or surfboard)
Have Fun!
We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).