Scientist I, ASO Process Development and Manufacturing
About The Position
We are seeking a highly motivated and creative individual to join our Oligonucleotide Chemical Development team as a Scientist I. This role is an exciting opportunity to develop robust processes for the synthesis of oligonucleotides, contributing significantly to both clinical and commercial therapeutics. You will gain hands-on experience in designing and developing manufacturing processes, working closely with our development and manufacturing teams. Your efforts will enhance process robustness, productivity, and impurity control, bringing substantial value to our work in oligonucleotide synthesis. As part of the larger Biogen structure, your contributions will play a pivotal role in advancing our scientific endeavors and impacting patient outcomes.
Requirements
- M.S. with 0-2 years of relevant experience in pharmaceutical or biotech settings.
- B.S with more than 3 years of relevant experience in pharmaceutical or biotech settings.
- Specialization in synthetic organic chemistry, with excellent synthetic skills and a deep understanding of reactivity and reaction mechanisms.
- Ability to work both independently and collaboratively, with effective communication skills in written and oral forms.
- Self-driven, independent thinker, vigorous and thorough in experimentation and data interpretation.
Nice To Haves
- Experience in nucleoside chemistry or oligonucleotide synthesis.
- Perform synthetic process research and development of drug candidates and conjugates.
- Continuous improvement mindset for research projects and synthesis processes.
Responsibilities
- Collaborate with development and manufacturing teams to design and conduct laboratory experiments to optimize synthesis processes.
- Perform ASO pilot-scale syntheses to support preclinical studies.
- Accurately record experimental procedures and data.
- Communicate research results effectively through writing reports and presenting in meetings.
- Engage in CMC activities, including authoring CMC sections of INDs.
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
