Scientist I - ADME Tox
About The Position
The Scientist I will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry method development and analysis, with related experience in a contract research organization (CRO) or industry laboratory. The role involves performing work in a laboratory setting, providing leadership and mentorship for junior scientists, and managing daily lab operations, equipment, and planning. Key responsibilities include developing Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications, developing analytical methods for new assay development, troubleshooting and maintaining Mass Spectrometers and HPLC units, preparing and managing inventory, providing solutions to complex problems, initiating process improvements, performing data and report QC review, and supporting the validation of new methods.
Requirements
- 3+ years of of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas: Bioanalytical Method Development for Small and/or Large Molecules, Drug Metabolism and Metabolite Identification w/ Structural Elucidation, Mass Spectrometry-Based Proteomics experimental design & execution
- Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
- Experience working in a Quality Management System.
- Demonstrated proficiency in High-Throughput analytical method development for small molecules.
- Experience in leading and delivering results in R&D or innovation programs.
- Demonstrated experience leading in human mammalian cell culture laboratories.
- Demonstrated experience working with light-based readers with 384-well and 96-well plates.
- B.S. with 3 years of relevant experience
- M.S. with 2 years of relevant experience
- Ph.D. with 1 years of relevant experience
- Or an equivalent combination of education and experience
- Ability to work in the U.S. indefinitely without sponsorship or restriction
Nice To Haves
- Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
Responsibilities
- Perform work in a laboratory setting and meets the physical job requirements of a lab role.
- Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
- Develop Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications
- Develop analytical methods supporting project teams both internally and externally for new assay development.
- Perform Troubleshooting and Maintenance of Mass Spectrometers and HPLC units.
- Prepare and manages inventory of buffers, reagents, semi-finished and finished goods.
- Provide solutions to more complex problems, identifies and initiates process improvements
- Perform data and report QC review within the department and may support the Study Director.
- Support validation of new methods that contribute to expansion of service/product line, equipment, and data management systems.
Benefits
- comprehensive medical coverage
- dental
- vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
