Scientist - HTS Oligo Synthesis

Merck • Billerica, MA

18h

About The Position

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: EMD Serono in Billerica, MA is seeking a Scientist – HTS Oligo Synthesis to add to their Oligonucleotide Therapeutics Group (DDTech).

Requirements

• Minimum Qualifications: PhD in Chemical Engineering, Chemistry, Biochemistry or other Science discipline OR Master’s degree in Chemical Engineering, Chemistry, Biochemistry or other Science or Engineering discipline with 3+ years of experience in oligonucleotide field OR Bachelor’s degree in Chemical Engineering, Chemistry, Biochemistry or other Science or Engineering discipline with 5+ years of experience in oligonucleotide field

Nice To Haves

• Good understanding of Oligonucleotide chemistry
• Experience with a wide range of Oligo purification/analytical techniques, especially HPLC and/or HPLC-MS
• Experience performing desalting by using gel filtration or membrane filtration techniques
• High degree of flexibility and motivation in a fast-paced work environment

Responsibilities

• Synthesis of oligonucleotides, deprotection, purification, desalting and lyophilization of oligonucleotides
• Operate Expedite/ABI/Mermade synthesizers and HPLC systems
• Prepare oligonucleotide synthesis reagents and synthesize, process, and purify ASO/siRNA using automated instruments by anion-exchange and reverse-phase HPLC systems
• Desalt, concentrate, and lyophilize final Oligo’s material using appropriate instrumentation or techniques
• Maintain a well-documented laboratory notebook and follow the safe laboratory practices
• Operate and troubleshoot available instruments including HPLC and MS
• Maintain an electronic laboratory notebook and miscellaneous documentation and maintain reagent inventory

Benefits

• Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.
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• We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace.
• Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree