Scientist, Drug Product Process Development (Contract)

Allogene Therapeutics • South San Francisco, CA

3d • Onsite

About The Position

Allogene Therapeutics is a clinical-stage biotechnology company developing allogeneic CAR T products for cancer and autoimmune disease. The Scientist will support development and characterization of clinical-scale manufacturing processes for Allogene’s CAR T therapies, helping implement state-of-the-art processing technologies and deliver scalable, robust processes. The role also supports successful technology transfer for GMP manufacturing and release and contributes to development of novel technologies and approaches for future manufacturing needs.

This is a one-year contract opportunity, with the possibility of extension or contract-to-hire. The expected hourly pay range is $50 to $58; actual pay depends on experience, qualifications, geographic location, business needs, and other permitted job-related factors. The role is onsite, as indicated by the job posting’s onsite tag. Candidates must be authorized to work in the United States.

Requirements

• Bachelor’s degree in Chemical Engineering, Biochemistry, Molecular and Cell Biology, Immunology, or a related field, plus at least 8 years of process development experience; or a master’s degree plus at least 5 years of process development experience.
• Foundational understanding of mammalian or primary cell culture, biochemistry, and molecular and cell biology.
• Ability to execute technical projects involving complex problem solving and critical thinking.
• Ability to work in a fast-paced startup environment.
• Strong attention to detail and ability to multitask and manage multiple responsibilities.
• Strong organizational skills and ability to prioritize effectively and deliver results within established timelines.
• Ability to work independently and as part of a team.
• Strong interpersonal skills, including verbal and written communication skills.
• Authorization to work in the United States.

Nice To Haves

• Experience in gene and cell therapy manufacturing or process development.
• Experience with JMP Design of Experiments methodologies in biologics or cell therapy.
• Experience with continuous manufacturing processes, including upstream genetic modification, bioreactor or WAVE expansion, and cryopreservation.

Responsibilities

• Contribute to development, implementation, characterization, and execution of robust, state-of-the-art CAR T manufacturing processes.
• Execute and analyze Design of Experiments studies, ideally using JMP software, to support process understanding, optimization, and characterization.
• Support clinical-scale non-GMP manufacturing operations for BLA-enabling process characterization activities.
• Contribute to process characterization and continuous improvement initiatives, including evaluation of process parameters, materials, closed or disposable systems, and operational workflows.
• Contribute to Project Technical Teams and collaborate and communicate effectively with stakeholder groups.
• Maintain high-quality, timely documentation in electronic laboratory notebooks and technical reports, and contribute to regulatory filings and responses to regulatory questions as appropriate.
• Present data and strategies to scientists and management in internal technical and project team meetings as appropriate.
• Stay current with relevant cell therapy, immunology, and bioprocessing literature.
• Perform other duties as assigned.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior