Scientist, Discovery Pharmaceutics

Johnson & Johnson Innovative MedicineSan Diego, CA
$76,000 - $121,900Onsite

About The Position

This laboratory-based role is focused on generating high-quality data to support Discovery programs across our synthetic portfolio, including small molecules, degraders, peptides, and oligonucleotides. In this position, you will design and complete experiments, provide technical insight to Discovery teams to inform molecular design and drug delivery strategies, and support the identification and selection of appropriate solid-state forms of active pharmaceutical ingredients (APIs). You will also develop and manufacture conventional and enabling formulations to support pharmacology, pharmacokinetic, and toxicology studies. The successful candidate will thrive in a multidisciplinary, collaborative environment and make significant contributions to innovative drug discovery programs.

Requirements

  • Minimum of a B.S. degree in Pharmaceutical Sciences, Chemistry, Biological Sciences, Analytical Sciences, or a related discipline is required
  • Minimum 1 year of hands-on industry laboratory experience in formulation, preformulation, analytical testing, physicochemical characterization, or a related pharmaceutical sciences area.
  • Hands-on experience with HPLC/UPLC methods for the quantitative and qualitative analysis of drug substances and formulations.
  • Ability to execute assigned laboratory studies using established procedures, generate reproducible data, and identify routine technical issues with appropriate guidance
  • Ability to learn quickly, follow prescribed guidelines, and contribute to straightforward research tasks within a collaborative, matrixed team environment.
  • Strong attention to detail, commitment to data quality, and ability to accurately document and communicate experimental results within the immediate team.
  • Ability to conduct hands-on laboratory work safely and in compliance with internal standards, procedures, and documentation expectations.
  • Basic proficiency with digital tools for data capture, analysis, visualization, and electronic laboratory notebook documentation.
  • Demonstrated ability to collaborate effectively across functions.

Nice To Haves

  • Experience designing, manufacturing, and characterizing amorphous solid dispersions.
  • Hands-on experience conducting small-scale crystalline form identification screens and using characterization techniques such as PXRD, DSC, TGA, and polarized light microscopy.
  • Fundamental understanding of pharmaceutical science and preformulation, physicochemical properties.
  • Scientific curiosity, accountability, and adaptability, with the ability to navigate evolving scientific challenges with initiative, leadership, and a strong drive to deliver results.

Responsibilities

  • Conduct routine and non-routine laboratory experiments, interpret data, and draw scientifically sound conclusions.
  • Contribute to technical documentation and reports and maintain electronic laboratory notebooks in compliance with internal policies and quality standards.
  • Proactively identify, investigate, and troubleshoot issues related to data quality, experimental procedures, or instrumentation.
  • Leverage digital tools, data analytics, and computational approaches to enhance interpretation of experimental data, improve developability assessments, and accelerate decision-making in Discovery programs.
  • Collaborate effectively with cross-functional partners.

Benefits

  • medical
  • dental
  • vision
  • life insurance
  • short and long-term disability
  • business accident insurance
  • group legal insurance
  • consolidated retirement plan (pension)
  • savings plan (401(k))
  • Vacation –120 hours per calendar year
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Washington – 56 hours per calendar year
  • Holiday pay, including Floating Holidays –13 days per calendar year
  • Work, Personal and Family Time - up to 40 hours per calendar year
  • Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
  • Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member
  • Caregiver Leave – 10 days
  • Volunteer Leave – 4 days
  • Military Spouse Time-Off – 80 hours
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year
  • Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
  • Caregiver Leave – 80 hours in a 52-week rolling period
  • Volunteer Leave – 32 hours per calendar year
  • Military Spouse Time-Off – 80 hours per calendar year
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