Scientist 1, Oligonucleotide Chemist (Synthesis & Purification)

BioMarin PharmaceuticalSan Rafael, CA
Onsite

About The Position

BioMarin is seeking a dedicated and skilled Scientist specializing in oligonucleotide synthesis to contribute to our cutting-edge research and development efforts in nucleic acid-based therapeutics. This role offers a unique opportunity to be part of a dynamic team at the forefront of biotechnology innovation, working on projects that have the potential to transform patient outcomes.

Requirements

  • PhD degree in Chemistry with 0-2 years of industry experience or Master’s degree with 8-10 years in the biotech or pharmaceutical industry.
  • Demonstrated ability to work independently as well as part of a collaborative team environment, with a proactive approach to problem-solving and advancing research programs.
  • Strong enthusiasm for scientific research and innovation, coupled with excellent organizational skills and the ability to manage multiple tasks and projects simultaneously.
  • Commitment to maintaining up-to-date knowledge of advancements in oligonucleotide chemistry and related fields, with a willingness to engage in ongoing professional development.
  • Expertise in solid-phase oligonucleotide synthesis and purification, with a strong track record of successful project outcomes.
  • Excellent written and verbal communication skills, with the ability to effectively present data and findings to both technical and non-technical audiences.

Responsibilities

  • Engage actively in project team discussions across the organization, providing subject matter expertise to support the progression of research projects and the development of new methodologies.
  • Work synergistically with multidisciplinary teams, including bioconjugation specialists, chemists, and biologists, to drive project success and foster a collaborative research environment.
  • Execute oligonucleotide synthesis utilizing automated solid-phase synthesis methodologies to ensure high-quality and reproducibility of synthesized oligonucleotides.
  • Conduct purification of synthesized oligonucleotides via high-performance liquid chromatography (HPLC) and other relevant techniques to achieve the desired purity and quality standards.
  • Maintain comprehensive and meticulous records of experimental protocols, results, and data analyses, ensuring data integrity and compliance with regulatory standards.
  • Contribute to the maintenance of a safe and compliant working environment, adhering to all health and safety regulations and promoting a culture of safety within the laboratory.
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