RNA-LNP Process Development - Lab Coordinator

Eurofins USA PSS Insourcing Solutions•Boston, MA

9d•Onsite

About The Position

We are seeking a Lab Manager to support a LNP and RNA Process Development team. The successful candidate will have a passion for driving efficient lab operations through excellence in lab equipment maintenance, raw material inventory management, and execution of routine analytical assays. The successful candidate will have a desire to contribute to a team focused on establishing science-based manufacturing solutions for complex nucleic acid-based products. Maintain a safe and high performing laboratory. Support continuous improvement initiatives related to lab operations. Build and maintain process development specific raw material and consumables inventory systems. Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes. Maintain detailed preparation records in an electronic lab notebook (ELN). Assist with routine maintenance tracking and upkeep of laboratory equipment used in process development. Build and maintain equipment maintenance program for Agilent HPLC, Akta Avant preparative liquid handling, and capillary gel electrophoresis (CGE) systems. Opportunity to perform routine analytical tests to support understanding of RNA technology and processes; analytical assays include HPLC, CGE, and ELISA-based methods. Opportunity to write lab maintenance protocols, SOPs, contribute to the weekly lab operations meeting, and track and analyze lab efficiency metrics. Opportunity to collaborate with external vendors and cross-functional teams including analytical development, as well as the facilities and operations team.

Requirements

B.S./MS degree in biological sciences, chemistry, or biomedical/chemical engineering (or related field) with at least 3 years of relevant industry laboratory experience
Experience with the operation and maintenance of equipment commonly used in the process development of nucleic acids, including Atka Avant chromatography systems and Agilent HPLC systems.
Knowledge of inventory management systems and reagent/buffer preparation best practices.
Strong understanding of laboratory operations and safety protocols.
Proven ability to manage multiple priorities and work independently.
Excellent organizational skills and attention to detail.
Self-motivated with the ability to identify and solve problems proactively.
Ability to coordinate with scientists, vendors, and service providers.
Proficiency with MS Office Suite (Word, PowerPoint, Excel).
Strong work ethic and excitement for being part of an integrated operations team.
Must be able to work in an active lab environment.

Nice To Haves

Knowledge of nucleic acid (mRNA, gRNA), LNP, and/or biologics process development.
Knowledge of analytical methods used for nucleic acid and/or biologics process development, including HPLC, CGE, or ELISA experience.
Authorization to work in the United States indefinitely without restriction or sponsorship.

Responsibilities

Maintain a safe and high performing laboratory.
Support continuous improvement initiatives related to lab operations.
Build and maintain process development specific raw material and consumables inventory systems.
Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes.
Maintain detailed preparation records in an electronic lab notebook (ELN).
Assist with routine maintenance tracking and upkeep of laboratory equipment used in process development.
Build and maintain equipment maintenance program for Agilent HPLC, Akta Avant preparative liquid handling, and capillary gel electrophoresis (CGE) systems.
Perform routine analytical tests to support understanding of RNA technology and processes; analytical assays include HPLC, CGE, and ELISA-based methods.
Write lab maintenance protocols, SOPs, contribute to the weekly lab operations meeting, and track and analyze lab efficiency metrics.
Collaborate with external vendors and cross-functional teams including analytical development, as well as the facilities and operations team.