Research Technologist I - Cell Biology, Neurobiology and Anatomy

Medical College of Wisconsin•Milwaukee, WI

11d•Onsite

About The Position

This individual will be trained to conduct a screen using zebrafish to identify compounds with therapeutic potential to prevent the retinal photoreceptor degeneration associated with Usher Syndrome type 1B/ MYO7A mutations. In addition, they will conduct molecular genetic experiments to address which isoforms of Myo7A might rescue photoreceptor degeneration in a zebrafish model of USH1B. They will work under general supervision of the PI and also be responsible for general laboratory maintenance, execution of other experiments, and documentation / communication of data.

Requirements

Knowledge of molecular biology, genetics, chemistry, mathematics, documentation, and records management.
Hands on experience with molecular / cellular biology and microscopy preferred.
Data utilization, complex problem solving, critical thinking, resource management, and writing skills.
Prior experience with experimental animal models is preferred.
Bachelor’s degree
No experience

Nice To Haves

Hands on experience with molecular / cellular biology and microscopy
Prior experience with experimental animal models
1-2 years of prior research experience recommended/preferred (particularly with molecular biology)

Responsibilities

Generate gene expression plasmids and use those to establish transgenic zebrafish lines.
Carry out zebrafish husbandry and transgenic/mutant line maintenance.
Conduct a chemical compound screen for potential therapeutics using a zebrafish model of USH1B.
Collect, document, and evaluate confocal microscopic retinal images as part of the USH1B compound screen.
Record and compile accurate records and communicate summaries of experimental results.
Assist with the evaluation, interpretation and assessment of experimental data.
Participate in meetings with principal investigator and research staff and evaluate/interpret the validity of data as needed.
Oversee daily project operation in the absence of the supervisor or Principle Investigator.
Participate in training new lab personnel including graduate students and post-doctoral fellows.

Benefits

Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental.
Flexible Spending options
403B Retirement Package
Competitive Vacation and Paid Holidays offered
Tuition Reimbursement
Paid Parental Leave
Employee & Family Assistance Program (EFAP)
Pet Insurance
On campus Fitness Facility, offering onsite classes
Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.