RESEARCH TECHNICIAN - Lippi Lab

Scripps Research • San Diego, CA

30d • $19 - $24 • Onsite

About The Position

The Lippi lab at Scripps Research seeks a
Research Technician
as part of a
growing team of investigators studying how post-transcriptional mechanisms
instruct brain development and function. We have pioneered new conceptual and
technological frameworks to interrogate these mechanisms, including inducible
and reversible global microRNA loss-of-function, cell type–specific
microRNA–target interaction mapping, scalable manipulation of individual
regulatory elements, and single-cell, isoform-sensitive measurements of
translation in vivo
(Zolboot
et al. Neuron 2025; Sison et al. Nature 2026).
For
more details please visit:
www.lippilab.org [http://www.lippilab.org/]

As a Research Technician, you will support Postdoctoral Fellows and Graduate
Students
who
are
using
these tools to discover fundamental new biology.
This
position offers the opportunity to collaborate with a talented team, present
findings in lab meetings,
author scientific papers,
and contribute to exciting
discoveries.

Requirements

• Requires a bachelor's degree in a relevant scientific discipline.
• Candidates at both junior and senior experience levels are encouraged to apply.
• At least three (3) years of related laboratory experience is required for more experienced candidates.

Nice To Haves

• Mouse primary neuronal culture preparations (e.g., cortical or MGE preps), brain injections in embryos and in early postnatal pups, brain slice preparation, and AAV and LV production.
• Establishing and optimizing CRISPR screens (e.g., CRISPRa/i), molecular biology (cloning, viral vector design, biochemistry), iPSC-derived neurons, and flow cytometry.

Responsibilities

• Ensure laboratory personnel are maintaining a clean, organized workspace, upkeep laboratory inventory by ordering reagents and other supplies and place maintenance requests for laboratory apparatus and facility.
• Participate in weekly lab meetings by reporting data and presenting during journal clubs.
• Assist with multiple research projects under the guidance of research staff and graduate students.
• Prepare weekly mouse cortical neuron cultures and maintain these cultures, routinely handle mice for injections and sample collection; Section mouse brain tissue with vibratome and cryostat.
• Independently perform various research procedures including but not limited to immunohistochemistry, confocal microscopy, PCR, and DNA cloning.
• Collect and organize accurate data; perform statistical analyses and prepare graphs.

Benefits

• Employer Contributed Retirement Plan – Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) (which is similar to a 401(k) using your own pre or post-tax dollars)
• Full Suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more
• Access to Flexible Spending Accounts (Medical/Dependent Care)
• Competitive vacation and sick leave policies
• Free, on-site parking

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level