Research Technician II

Duke Careers•Durham, NC

1d•Hybrid

About The Position

Dr. Brad Goldstein’s Olfactory Neuroscience Lab in the Department of Head and Neck Surgery and Department of Neurobiology at Duke University is seeking a Research Associate, to help provide general assistance and contribute to basic and clinical research in the lab. This is a full-time position, eligible for all Duke benefits with an initial appointment term of one year with the possibility of renewal, dependent on performance and funding. The Goldstein Lab focuses on the study of neurogenesis and tissue renewal in the olfactory mucosa, in an effort to develop strategies to prevent or treat disorders that cause olfactory damage or loss. We use mouse models, cell culture approaches and human nasal tissue specimens. The lab utilizes multiple approaches to identify mechanisms regulating adult basal stem and progenitor cells in the olfactory epithelium, as well as olfactory tissue maintenance and renewal. We hold specific expertise in single cell RNA sequencing and have pioneered biopsy-based approaches for scSeq of human olfactory tissue. Our overall goal is to understand the cellular and molecular mechanisms causing acquired human olfactory disorders. Recently, we have undertaken projects focused on olfactory loss due to neurodegenerative diseases, including Alzheimer’s Disease, in collaboration with the Duke ADRC. Another collaborative project is focused on understanding olfactory neuroblastoma, a rare malignant tumor arising from the olfactory region.