The Choi Lab is seeking a Research Technician to work on T cell biology in mouse models of diseases, including, but not limited to, graft-vs-host disease (GvHD), inflammatory bowel disease (IBD), and/or experimental autoimmune encephalomyelitis (EAE). Using unbiased genome-wide CRISPR/Cas9 guide RNA library screens and whole kinome analyses, we have identified promising novel therapeutic targets such as VLDLR, GAS6/TAM, and PKN1 whose targeting may separate the inflammatory diseases from the beneficial healthy immune responses, such as graft-vs-leukemia/tumor effects, anti-tumor and anti-infection responses. Assists with the technical aspects of studies and experiments, including documentation and preparation of materials. Mouse handling is required. For translational approaches, may occasionally analyze human patient samples.
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Job Type
Full-time
Career Level
Mid Level