Research Technician I

Bexorg•New Haven, CT

6d•$29•Onsite

About The Position

Bexorg is a precision neurology company working to improve how new medicines for central nervous system (CNS) diseases are discovered and developed. Its work brings together neuroscience, AI, engineering, and translational drug development, with an emphasis on scientific rigor, responsible stewardship, and cross-disciplinary collaboration. The Research Technician I will maintain human brain slice and cell cultures and perform daily bench work supporting drug studies. Senior staff will train the technician in the methods, with the goal of building toward independent assay work. The role is suited to an early-career lab professional who is careful, reliable, and interested in learning imaging and tissue methods. The position is full-time and on-site in New Haven, Connecticut, with rotating night shifts and weekend work.

Requirements

Bachelor’s degree in biology, neuroscience, biomedical engineering, or a related field; alternatively, an associate degree with relevant hands-on laboratory experience.
0–2 years of laboratory experience, including internships, co-ops, or laboratory courses.
Hands-on experience with sterile cell or tissue culture.
Basic laboratory skills, including accurate pipetting, solution preparation, and use of plate readers or similar instruments.
Careful and consistent record keeping.
Willingness to work rotating night shifts and weekends.
Comfort working with human post-mortem tissue under biosafety level 2 (BSL-2) practice; training is provided.
A can-do attitude.

Nice To Haves

Hands-on experience with fluorescence microscopy, cryosectioning, qPCR, RNAscope, CellTiter-Glo, pyruvate or lactate assays, or drug screening.
Experience with primary cells, tissue samples, or neural cultures.
Comfort with Excel and basic image tools such as Fiji (ImageJ).

Responsibilities

Care for organotypic human brain slice cultures and cell cultures, including media changes, drug dosing, and daily checks using strict sterile technique.
Prepare media, buffers, reagents, and drug plates according to written protocols.
Run plate-based assays, including CellTiter-Glo viability and pyruvate and lactate measurements from culture media.
Stain slices with live fluorescent dyes and image them using a widefield fluorescence microscope and slide scanner, following established protocols.
Cut 8–20 µm cryosections from fixed slices using a cryostat, mount them, and assist with immunofluorescence staining.
Support qPCR work, including RNA extraction and plate setup, and perform RNAscope in situ hybridization runs under supervision.
Assist with drug-screening experiments in multi-well plates by following plate maps and dosing schedules.
Accurately record samples, treatments, and results in sample-tracking and data systems.
Support laboratory operations, including stock and inventory management, equipment cleaning, waste handling, and safety upkeep.
Work rotating night shifts and weekends to keep cultures and assays on schedule.