Research Tech I

Mass General Brigham•Boston, MA

8d•$21 - $29•Onsite

About The Position

We are seeking a bright and highly motivated individual interested in developing skills and experience in biomedical and translational research as a research assistant at the Massachusetts General Hospital Cardiovascular Research Center and Harvard Medical School in the laboratory of Paul B. Yu, M.D., Ph.D. The laboratory is dedicated to pursuing a deep cellular and molecular understanding of how dysregulated signaling regulates cell survival and differentiation in congenital and acquired vascular, metabolic, and musculoskeletal diseases. The lab is dedicated to understanding how intercellular signaling is interpreted in specific contexts to modify wound-healing, inflammation, and regeneration to yield productive or maladaptive tissue remodeling. We utilize novel animal models of disease, chemical probes and reporter systems, as well as computational biology and bioinformatic techniques for analyzing large datasets from human clinical databases. Our work has recently led to novel treatments and diagnostic tests that have entered clinical testing. The candidate will be trained in basic science and translational study methods, and potentially work with patients in the context of several ongoing pilot clinical studies. Our work lies at the nexus of progenitor cell biology, chemical biology, cardiovascular physiology, and experimental pharmacology. We welcome applications from intellectually curious individuals with an interest in developing their skills towards careers in Health Sciences, Research, or Drug Development. Recent trainees have followed their work in the laboratory with subsequent Medical School and Clinical training (M.D. and M.D./Ph.D. programs), Graduate School (Ph.D. programs), Medical and Research Faculty Positions, and Biotech and Pharma Industry Positions. Research assistants are expected to serve as co-authors for publications during their tenure, with previous members publishing in journals including Science Translational Medicine and American Journal of Respiratory and Critical Care Medicine.

Requirements

Bachelor's Degree Related Field of Study required
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred
Strong theoretical and practical knowledge of laboratory techniques and procedures.
Familiarity with common laboratory equipment and instruments used in research experiments.
Proficiency in data collection, analysis, and scientific software tools.
Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
Strong problem-solving skills and the ability to troubleshoot technical issues.
Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Nice To Haves

Can this role accept experience in lieu of a degree? Yes

Responsibilities

Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.