Research Specialist I

Altos Labs • San Francisco, CA

3h

About The Position

An exciting opportunity is available for a dedicated and highly skilled Research Specialist I to join the In Vivo Translational Operations (IVTS) team of Drug Discovery and Development (3DS) at Altos Labs. The successful candidate will be supporting the progression of our therapeutic programs by conducting and optimizing in vivo research activities and successful execution of preclinical studies. This role will collaborate closely with the Directors and Scientists to ensure the effective prioritization of projects, achievement of milestones, and overall operational excellence.

Requirements

• Master’s degree in life-science or related field or BA/BS with 8+ years of experience in pharmaceutical industry
• Broad and extensive expertise with all aspects of in vivo rodent research (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.) in both mice and rats
• 3Rs-centered, welfare-oriented approach to animal-based research
• Strong communication skills, essential for effective collaboration with cross-functional teams and CROs used for outsourced studies
• Exceptional organizational and attention to detail skills, with the capacity to work autonomously as well as in a team setting
• Ability to troubleshoot and effectively solve problems in a timely and efficient manner, demonstrating resourcefulness and a high level of analytical thinking

Nice To Haves

• Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable
• Experience analyzing age-related diseases/deficits in animal models; including inflammation, metabolic disorders, neurodegeneration, muscle atrophy, bone loss and/or joint deficits

Responsibilities

• Assist in planning, executing and managing in vivo studies (in both mice and rats), including protocol development, dosing and tissue collection, study monitoring, bio sample management, tissue processing and relevant data analysis
• Conduct survival surgeries to establish various rodent models using aseptic techniques
• Collaborate in the development, characterization and implementation of new animal models to improve the effectiveness of in vivo pharmacology studies
• Provide critical input for the development of project-specific approaches, adapting techniques and procedures to incorporate emerging technologies and best practices
• Contribute to enhancing the lab's efficiency and impact through the development of workflows and innovative experimental strategies
• Maintain detailed documentation of all studies in electronic lab notebook to ensure data integrity and traceability
• Collaborate with cross-functional teams, including Institute of Sciences, In Vitro Pharmacology, Science Integration, Innovation and Insights, Drug Metabolism and Pharmacokinetics, etc. to support the development and progression of therapeutic programs
• Ensure compliance with regulatory guidelines and ethical standards in the conduct of in vivo studies
• Contributes to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Benefits

• Equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Associate degree