Research Scientist

UT Health San Antonio•San Antonio, TX

About The Position

Under the general supervision of Dr. Mengwei Zang at UT Health San Antonio, the Research Scientist will support the day-to-day operations of an NIH-funded R01 research study. The role focuses on nutrient sensors in metabolic liver disease and aging, including identifying molecular mechanisms that regulate cell metabolism and contribute to alcoholic liver disease, metabolic liver disease, and aging. The successful candidate will plan, conduct, analyze, and report research; perform animal studies; support grant applications; and prepare scientific publications.

Requirements

  • A specific professional doctoral degree and five years of relevant research experience are stated as required in the description.
  • A master's degree in a related field is required.
  • Two years of related experience is required.
  • Evidence of peer-reviewed scientific publications in the relevant field of specialization is required.
  • Ability to coordinate tasks, manage multiple complex research projects simultaneously, and apply strong organizational and time-management skills.
  • Ability to maintain transgenic mouse colonies, including breeding, weaning, and genotyping; establish and maintain mouse disease models; and administer experimental treatments.
  • Ability to troubleshoot experimental protocols independently.
  • Ability to maintain accurate research records, work independently, and collaborate effectively within a multidisciplinary research team.
  • Effective verbal and written communication skills, including the ability to prepare scientific manuscripts, research proposals, study reports, and official correspondence.
  • Proficiency in Microsoft Word, Excel, PowerPoint, GraphPad Prism, OneNote, and email applications, and willingness to learn study-specific software.

Nice To Haves

  • A doctorate in a related field is highly preferred.
  • Five years of related experience is highly preferred.

Responsibilities

  • Initiate and participate in the design, execution, and evaluation of innovative research projects on nutrient sensors in metabolic liver disease and aging.
  • Manage ongoing projects initiated by the principal investigator, focusing on molecular mechanisms regulating cell metabolism and contributing to alcoholic liver disease, metabolic liver disease, and aging.
  • Generate and analyze preliminary data to support grant applications to federal agencies and foundations.
  • Develop and implement technical methodologies, including PCR, real-time PCR, cell culture and transfection, Western blotting, histological analysis, and tissue staining.
  • Develop analysis plans and statistical analysis strategies for advanced RNA-sequencing (RNA-seq) data analyses, and organize and maintain research databases.
  • Author and co-author scientific publications, present research findings at meetings and conferences, and contribute to study protocols and research reports.
  • Coordinate preparation of grant applications with designated investigators and research collaborators, and prepare applications independently.
  • Supervise students and researchers.
  • Conduct animal studies and support day-to-day operations of the NIH-funded R01 research study.
  • Perform all other duties as assigned.
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