Research Scientist

NYU Langone HealthNew York, NY
$70,000 - $85,000Onsite

About The Position

The Translational Aging Neurogenetics Laboratory (TANGL), led by Anil R. Wadhwani, MD, PhD, is seeking an experienced Research Scientist to help establish and grow its experimental program in human stem-cell models of brain aging and neurodegenerative disease. TANGL integrates human genetics and epigenomics, biomarkers, longitudinal cohorts, computational models, and experimental biology to understand why some people remain resilient despite aging or disease. We aim to translate those discoveries into new approaches for preserving brain health.

Requirements

  • PhD (preferred) or MS with 2-4 years of experience in a relevant field (including but not limited to neuroscience, genetics, molecular biology, or stem cell biology)
  • Substantial hands-on experience in mammalian cell culture, stem-cell biology, molecular neuroscience, or disease modeling.
  • Ability to design, execute, troubleshoot, and document complex experiments with independence.
  • Strong self-motivation, scientific judgment, organization, and follow-through.
  • A collaborative and generous mentoring style, with enthusiasm for cross-disciplinary science.
  • A genuine passion for understanding human genetics or brain aging, and a desire to promote and preserve brain health.
  • MS degree and 2-4 years of experience or equivalent combination of education and experience.
  • Qualified candidates must be able to effectively communicate with all levels of the organization.

Nice To Haves

  • Expertise in iPSC neural models, CRISPR or epigenome editing, high-content imaging, electrophysiology, single-cell methods, or multiomic assays.
  • Experience building a new laboratory workflow or supervising research staff.

Responsibilities

  • Establish and optimize human iPSC culture, quality control, banking, and neural differentiation workflows.
  • Lead CRISPR-based genome and epigenome perturbation studies.
  • Design and troubleshoot experiments focused on tau biology, neuronal vulnerability, and resilience.
  • Develop molecular, imaging, neurite, synaptic, viability, and functional phenotyping assays.
  • Create practical SOPs for cell culture, contamination monitoring, reagent tracking, and data quality.
  • Coordinate projects, cores, collaborators, and experimental timelines.
  • Mentor trainees and help shape TANGLs scientific and collaborative culture.

Benefits

  • financial security benefits
  • a generous time-off program
  • employee resources groups for peer support
  • holistic employee wellness program, which focuses on seven key areas of well-being: physical, mental, nutritional, sleep, social, financial, and preventive care.
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