Research Scientist

University of Colorado•Aurora, CO

2d•Onsite

About The Position

We are seeking a highly motivated and interdisciplinary Research Scientist with experience in molecular biology, genomics, and translational research. This role includes basic science discovery and clinical application, advanced experimental systems, and human-derived samples to drive therapeutic innovation. The ideal candidate will excel in designing and executing complex experiments, managing research programs, and collaborating across clinical and scientific teams to translate insights into impactful outcomes.

Requirements

PhD in Molecular Biology, Pharmacology, Genetics, or related life sciences field.
3+ years of experience in translational or biomedical research.
Must successfully pass a drug test through Children’s Hospital Colorado
Must be willing and able to pass a national criminal background check

Nice To Haves

3 to 6 years of experience in immunology, respiratory biology, neuroscience, or human genetics.
5 years of experience in translational or biomedical research
Strong project and program management
Regulatory and quality compliance awareness
Data integrity and reproducibility focus

Responsibilities

Design, execute, and optimize cell-based and molecular biology assays including qPCR, ELISA, high-content imaging, and next-generation sequencing (NGS).
Develop and utilize 2D/3D cell culture systems, including patient-derived organoids, to model disease biology and evaluate therapeutic candidates.
Perform functional characterization of genetic modifications, including CRISPR-Cas9–based gene editing workflows.
Apply statistical and experimental design (DOE) principles to improve assay robustness, scalability, and throughput.
Lead and manage multi-disciplinary research projects, aligning timelines, resources, and deliverables across teams.
Oversee laboratory workflows, quality control systems, and documentation practices.
Identify risks, troubleshoot experimental variability, and implement corrective strategies.
Contribute to budget planning, resource allocation, and operational efficiency within research programs.
Contribute to grant writing, publications, and scientific reports.
Mentor junior scientists and research staff, supporting technical development and career growth.
Provide leadership in laboratory operations, promoting a culture of innovation, accountability, and scientific excellence.
Lead cross-functional discussions, resolve project conflicts, and align teams toward shared goals.