Research Scientist, Lab Technician I or II

Novartis•Cambridge, MA
•$66,800 - $150,800•Onsite

About The Position

The Oncology Pharmacology group at BR in Cambridge, Massachusetts, is seeking a scientist proficient in in vivo techniques to support the development and characterization of novel therapeutics and targets. The role is based onsite in Cambridge and cannot be performed remotely. It is a dual posting; the final level and title will be determined by the hiring team based on skills, experience, and capabilities. The position involves in vivo work directly with rodents, including technical procedures and related pre-study laboratory and ex vivo activities. The employee is expected to follow standard operating procedures, policies, animal welfare regulations, and regulatory procedures; maintain data quality and meet timelines; and work safely in a BSL 1 and/or 2 laboratory. The role requires wearing appropriate PPE, standing for prolonged periods, performing repetitive motions, and working weekends or holidays when needed.

Requirements

  • GED or high school degree required.
  • At least 1 year of hands-on experience with in vivo procedures in rodents, including multiple dose-administration routes (IP, PO, IV, SC), blood and sample collection (cardiac, tail vein, saphenous), dissection techniques, and necropsies.
  • Demonstrated ability to learn quickly, multitask, and maintain good organizational skills.
  • Meticulous laboratory approach, with careful adherence to protocols and laboratory notebook documentation.
  • Familiarity with regulations and guidelines governing the humane use of animals in research.
  • Reliable, focused, attentive to detail, and able to work independently as well as in a dynamic team environment.
  • Highly motivated, with a sense of urgency and flexibility.
  • Excellent interpersonal and communication skills.
  • Able to wear appropriate PPE and physically perform technical procedures involving rodents; able to stand for prolonged periods and perform repetitive-motion tasks.
  • Able to work weekends or holidays when needed.

Nice To Haves

  • A two-year degree in Veterinary Technology or a four-year science degree, with at least 1 year of industry or academic experience, or a combination of experience and higher education.
  • Experience with cancer models, including xenografts or syngeneic models, and in vivo assays for pharmacokinetic evaluations.
  • Prior CRO experience.

Responsibilities

  • Perform in vivo procedures, including IV, IP, SQ, and PO dosing; body-weight measurements; clinical and in-life observations; sample and tissue harvests; necropsy; blood collection; and euthanasia.
  • Follow standard operating procedures, policies, animal welfare regulations, and regulatory procedures.
  • Assist with in vivo pharmacology pre-study laboratory activities and related ex vivo activities, including preparing and labeling consumables, placing orders, organizing reagent inventories, and processing samples.
  • Manage multiple assignments and projects while maintaining data quality and meeting timelines.
  • Maintain a safe working environment and comply with applicable safety regulations in a BSL 1 and/or 2 laboratory.
  • Ensure compliance with internal and external regulatory agencies in accordance with the Guide for the Care and Use of Laboratory Animals.

Benefits

  • Health benefits
  • Life benefits
  • Disability benefits
  • 401(k) with company contribution and match
  • Vacation
  • Personal days
  • Holidays and other leaves
  • Performance-based cash incentive
  • Eligibility for consideration for annual equity awards, depending on role level
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