Research Scientist

UNC-Chapel HillChapel Hill, NC
7d

About The Position

Dr. Gaorav Gupta’s laboratory at the UNC Lineberger Comprehensive Cancer Center is seeking a Research Scientist to assist in studying the role of DNA damage responses in breast cancer development and treatment response. This Research Scientist will design, execute, and analyze in vivo and in vitro experiments to study novel combination therapies in breast cancer mouse models, organoids, and primary mammary epithelial cell culture. Additional responsibilities will include management of our transgenic mouse colony including breeding, weaning, and genotyping, ordering lab supplies and general lab management, and assisting other lab members with experiments involving cellular and molecular biology methods. Required mouse handling techniques include intraperitoneal and retro-orbital injections, submandibular cheek bleeds, and oral gavage. The position will involve oversight/supervision of technicians and graduate students, and coordination of multiple research projects. Strong organizational skills, effective communication, and precise record keeping are required. In addition to carrying out these research projects, the research scientist will also be expected to lead efforts to present the results of these projects in lab meetings and conferences as well as assist in the authorship of manuscripts and grants. Thus, strong scientific communication skills are fundamental for this position.

Requirements

  • Experience with mouse colony management, mammalian tissue culture, and standard molecular biology techniques.
  • Proficiency in Word, Excel, and Powerpoint.
  • Exceptional organizational skills and record keeping.
  • Strong organizational skills, effective communication, and precise record keeping are required.
  • Strong scientific communication skills are fundamental for this position.
  • Required mouse handling techniques include intraperitoneal and retro-orbital injections, submandibular cheek bleeds, and oral gavage.

Nice To Haves

  • PhD in cancer biology, immunology, cellular/molecular biology, or a related field.
  • Experience in cell and molecular biology preferably in the study of DNA damage repair.
  • The candidate must also have proficiency in the isolation, culture, and manipulation of primary cells.
  • Experience with organoids and microscopy is preferred.
  • Must have solid knowledge in cancer biology, develop project concepts, as well as author manuscripts and grants in a collaborative, team-oriented environment.

Responsibilities

  • Design, execute, and analyze in vivo and in vitro experiments to study novel combination therapies in breast cancer mouse models, organoids, and primary mammary epithelial cell culture.
  • Management of our transgenic mouse colony including breeding, weaning, and genotyping
  • Ordering lab supplies and general lab management
  • Assisting other lab members with experiments involving cellular and molecular biology methods
  • Oversight/supervision of technicians and graduate students
  • Coordination of multiple research projects
  • Present the results of these projects in lab meetings and conferences
  • Assist in the authorship of manuscripts and grants

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Ph.D. or professional degree

Number of Employees

11-50 employees

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